03-0196-00
SMC® Human Total α-synuclein High Sensitivity Immunoassay Kit
Uses 100 µL per well of 1:200 diluted serum or plasma samples, or 1:10 diluted cerebrospinal fluid (CSF) samples.
Synonym(s):
Human α-synuclein, α-synuclein, Human total-α-synuclein, a-synuclein, total-a-synuclein
About This Item
Recommended Products
species reactivity
canine, rat, feline, mouse
manufacturer/tradename
SMC®
assay range
sensitivity: 1.95 pg/mL
(LLOQ of Total α-synuclein)
inter-assay cv: 14%
intra-assay cv: 9%
(five normal plasma samples run in triplicate by 3 different operators on 3 different days)
technique(s)
single molecule counting: suitable
General description
1) Elution buffer disrupts the sandwich, separating the labeled detection antibody for quantification.
2) The Erenna and SMCxPRO® immunoassay systems detect analytes using Single Molecule Counting (SMC®) technology.
Specificity
Specificity to the following species samples were tested with the following results:
Monkey – 100%
Cat – 100%
Rat – 100%
Mouse – 100%
Beagle – 100%
Cross Reactivity
Cross-reactivity to the following analytes were tested with the following results:
Tau – 0%UCHL1 – 0%
β-synuclein – 0%
γ-synuclein – 0%
Accuracy
CSF Recovery: 5 CSF samples spiked with average recovery of 96% and a range of 90-102%
Serum Recovery: 4 serum samples spiked with average recovery of 96% and a range of 93-98%
Plasma Recovery: 4 plasma samples spiked with average recovery of 96% and a range of 93-97%
Application
Packaging
Components
- Assay Buffer
- Total α-synuclein Coated Beads
- Standard Diluent
- Total α-synuclein Detection Antibody
- Total α-synuclein Standard
- 10X Wash Buffer
- Buffer D
- Elution Buffer B
Other Notes
- This new streamline kit has the following features:
- Improved options for sample prep and incubation
- Lyophilization protein standard for uniform shipping and storage condition
- Increased reagent volumes to accommodate automation
- Able to achieve assay specifications on both SMCxPRO® and Erenna.
Legal Information
Disclaimer
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Repr. 1B
Storage Class Code
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Listings
Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.
JAN Code
03-0196-00 :
03-0196-00:
Certificates of Analysis (COA)
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