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840032P

Avanti

Brain PS

Avanti Research™ - A Croda Brand

Synonym(s):

L-α-phosphatidylserine (Brain, Porcine) (sodium salt)

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About This Item

CAS Number:
383907-32-2
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (840032P-10mg)
pkg of 1 × 100 mg (840032P-100mg)
pkg of 5 × 100 mg (840032P-500mg)
pkg of 1 × 25 mg (840032P-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand

lipid type

phosphoglycerides

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[Na+]

InChI

1S/C42H80NO10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(44)50-35-38(36-51-54(48,49)52-37-39(43)42(46)47)53-41(45)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h18,20,38-39H,3-17,19,21-37,43H2,1-2H3,(H,46,47)(H,48,49);/q;+1/p-1/b20-18-;/t38-,39+;/m1./s1

InChI key

ALPKKMIPHGSQRX-NJZWBUMZSA-M

Application

Brain PS has been used in lipid standard material preparation, reporter assay and in the preparation of liposomes.

Biochem/physiol Actions

Phosphatidylserine is a lipid. It helps to increase the cognitive performance of rats and humans, having different levels of age-dependent memory problems or probable Alzheimer disease. It has the ability to block degeneration of the cholinergic neuronal population of the basal forebrain of aged rats. 90% of the phosphatidylserine decarboxylase activity is linked with mitochondria.

Packaging

5 mL Clear Glass Sealed Ampule (840032P-100mg)
5 mL Clear Glass Sealed Ampule (840032P-10mg)
5 mL Clear Glass Sealed Ampule (840032P-25mg)
5 mL Clear Glass Sealed Ampule (840032P-500mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

also commonly purchased with this product

Product No.
Description
Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

840032P-25MG:
840032P-100MG:
840032P-BULK:
840032P-500MG:
840032P-VAR:
840032P-10MG:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Characterization of brain phosphatidylserine decarboxylase: localization in the mitochondrial inner membrane
Percy AK, et al.
Archives of Biochemistry and Biophysics, 223(2), 484-494 (1983)
Bovine brain phosphatidylserine attenuates scopolamine induced amnesia in mice
Claro FT, et al.
Progress in Neuro-Psychopharmacology & Biological Psychiatry, 30(5), 881-886 (2006)
M Gangal et al.
Proceedings of the National Academy of Sciences of the United States of America, 96(22), 12394-12399 (1999-10-27)
Although the catalytic (C) subunit of cAMP-dependent protein kinase is N-myristylated, it is a soluble protein, and no physiological role has been identified for its myristyl moiety. To determine whether the interaction of the two regulatory (R) subunit isoforms (R(I)
Alzheimer's disease-associated TREM2 variants exhibit either decreased or increased ligand-dependent activation
Song W, et al.
Alzheimers Dement., 13(4), 381-387 (2017)
Measurement of Binding of Basic Drugs to Acidic Phospholipids using Surface Plasmon Resonance and Incorporation of the Data into Mechanistic Tissue Composition Equations to Predict Steady-state Volume of Distribution (Vss)
Small H, et al.
Drug Metabolism and Disposition, dmd-111 (2011)
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