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840055P

Avanti

Liver PC

Avanti Research™ - A Croda Brand 840055P, powder

Synonym(s):

L-α-phosphatidylcholine (Liver, Bovine)

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About This Item

CAS Number:
475662-36-3
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 25 mg (840055P-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 840055P

lipid type

phosphoglycerides
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O)=O

General description

Phosphatidylcholine (PC) has two fatty acid chains attached to a head group. Generally, PC has saturated fatty acid in the sn-1 position and unsaturated fatty acid in the sn-2 position. It has a quaternary ammonium group and a phosphate moiety in the head group, existing as a zwitterion in a wide range of pH.

Application

Liver PC is suitable for use:
  • as a standard for quantitation of tumor derived lipids by thin layer chromatography
  • in the preparation of liposomes to mimic mammalian membranes
  • in lipid vesicle preparation to study intravesicular transfer of α-tocopherol fluorescent derivative (NBD-Toc)

Biochem/physiol Actions

Phosphatidylcholine (PC) plays a key role in the synthesis of second messenger and signaling molecules like diacyl glycerol, lysophosphatidic acid, phosphatidic acid and arachidonic acid. Liver PC has a saturated to unsaturated fatty acid ratio of 0.91.

Packaging

5 mL Clear Glass Sealed Ampule (840055P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

840055P-25MG:
840055P-VAR:
840055P-BULK:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Noncovalently and covalently bound lipid on the receptor for immunoglobulin E
Kinet JP, et al.
Biochemistry, 24(25), 7342-7348 (1985)
Liposomes with diverse compositions are protected during desiccation by LEA proteins from Artemia franciscana and trehalose
Moore DS, et al.
Biochimica et Biophysica Acta - Biomembranes, 1858(1), 104-115 (2016)
Essentials of Medical Biochemistry: With Clinical Cases (2011)
Effect of bilayer phospholipid composition and curvature on ligand transfer by the alpha-tocopherol transfer protein
Zhang WX, et al.
Lipids, 44(7), 631-631 (2009)
The Kennedy pathway?de novo synthesis of phosphatidylethanolamine and phosphatidylcholine
Gibellini F and Smith TK
IUBMB Life, 62(6), 414-428 (2010)
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