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Safety Information

L050080

Sigma-Aldrich

Cap B

configured for PerkinElmer, configured for Polygen

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About This Item

UNSPSC Code:
12352200
NACRES:
NA.21

type

for DNA synthesis

Quality Level

100

product line

Proligo Reagents

form

liquid

storage condition

dry at room temperature

impurities

≤200 ppm water content (Karl Fischer)

color

clear

suitability

conforms to structure (GC, Formulation)

compatibility

configured for PerkinElmer
configured for Polygen

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General description

Cap B solution contains tetrahydrofuran (THF), pyridine, and N-methylimidazole (NMI). It is mixed in situ with Cap A solution during the capping (acetylation) reaction. Pyridine is applied as a mild base while NMI provides a powerful acylation catalyst.

Preparation Note

Tetrahydrofurane / N-Methylimidazole / Pyridine 8/1/1 (v/v/v)

Other Notes

Cap B solution, containing tetrahydrofuran (THF), pyridine and N-methylimidazole (NMI), is mixed in situ with Cap A solution during the capping (acetylation) reaction. Pyridine is applied as a mild base while NMI provides a powerful acylation catalyst.

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Repr. 2 - Skin Corr. 1B - STOT SE 3

Target Organs

Central nervous system, Respiratory system

Supplementary Hazards

EUH019

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

6.1 °F

Flash Point(C)

-14.4 °C

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PRTR

Class I Designated Chemical Substances

FSL

Group 4: Flammable liquids
Type 1 petroleums
Hazardous rank II
Water insoluble liquid

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

L054500-01:
L050250-01:4548173230467
L050080-4L:
L050400-01:4548173225548
L050080-6X200ML:4548173341644
L050400-04:
L050250-04:4548173240312
L050080-45L:
L050080-2L:
L050080-450ML:
L050080-6X450ML:4548173341651
L050200-04:4548173295411
L050080-200ML:
L053000-01:4548173240329
L050250-4N:4548173279008
L050400-4N:4548173279022
L050080-4X2L:
L050080-4X2.5L:4548173341637
L050080-2.5L:4548173341620

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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