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K401

Sigma-Aldrich

2-Ketobutyric acid

97%

Synonym(s):

2-Oxobutanoic acid, 2-Oxobutyric acid, α-Ketobutyric acid, Propionylformic acid

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About This Item

Linear Formula:
CH3CH2COCOOH
CAS Number:
Molecular Weight:
102.09
Beilstein:
1700514
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

97%

form

liquid

bp

84 °C/20 mmHg (lit.)

mp

30-34 °C (lit.)

storage temp.

2-8°C

SMILES string

CCC(=O)C(O)=O

InChI

1S/C4H6O3/c1-2-3(5)4(6)7/h2H2,1H3,(H,6,7)

InChI key

TYEYBOSBBBHJIV-UHFFFAOYSA-N

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Application

2-Ketobutyric acid can be used as a reactant to synthesize:
  • (S)-2-Aminobutyric acid via enzyme-catalyzed amination reaction.
  • L-Isoleucine by living cell reaction in the presence of ethanol.
  • 3-Ethyl-2-quinoxalinol from 1,2-diaminobenzene in the presence of sulfuric acid.
  • 3-Ethylbenzo[g]quinoxalin-2(1H)-one using 2,3-diaminonaphthalene in the presence of biocatalyst.

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Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

179.6 °F - closed cup

Flash Point(C)

82 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

K401-25G:
K401-10G:
K401-BULK:
K401-5G:
K401-VAR:


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Biorefinery applications of Corynebacterium glutamicum
Jojima T, et al.
Corynebacterium glutamicum, 149-172 (2013)
Fabrication of a microcapsule extinguishing agent with a core-shell structure for lithium-ion battery fire safety
Zhang W, et al.
Materials Advances, 2, 4634-4642 (2021)
Synthesis of potential chemotherapic quinoxalinone derivatives by biocatalysis or microwave-assisted Hinsberg reaction
Gris J, et al.
Tetrahedron Letters, 49, 1053-1056 (2008)
Synthesis of 2-(Quinoxalin-2-ylamino-benzotriazolyl) Pentanedioic Derivatives as Potential Anti-Folate Agents
Briguglio I, et al.
Journal of Heterocyclic Chemistry, 53, 1721-1737 (2016)
Nora Weber et al.
Microbial cell factories, 16(1), 51-51 (2017-03-25)
Saccharomyces cerevisiae (baker's yeast) has great potential as a whole-cell biocatalyst for multistep synthesis of various organic molecules. To date, however, few examples exist in the literature of the successful biosynthetic production of chemical compounds, in yeast, that do not

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