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202789

Sigma-Aldrich

Beryllium sulfate tetrahydrate

99.99% trace metals basis

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About This Item

Linear Formula:
BeSO4 · 4H2O
CAS Number:
7787-56-6
Molecular Weight:
177.14
EC Number:
236-842-2
MDL number:
MFCD00149156
UNSPSC Code:
12352302
PubChem Substance ID:
24852118
NACRES:
NA.22

Assay

99.99% trace metals basis

density

1.713 g/mL at 25 °C (lit.)

SMILES string

[Be++].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[O-]S([O-])(=O)=O

InChI

1S/Be.H2O4S.4H2O/c;1-5(2,3)4;;;;/h;(H2,1,2,3,4);4*1H2/q+2;;;;;/p-2

InChI key

DIMYTQPLZWDZFE-UHFFFAOYSA-L

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Application

Used in study of the dicarboxylate chelation of beryllium in an attempt to understand its physiological chemistry.

Signal Word

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Carc. 1B Inhalation - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 1 Inhalation - STOT SE 3

Target Organs

Respiratory system, Skin,Respiratory Tract

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PRTR

Specified Class I Designated Chemical Substances

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

202789-BULK:
202789-50G:4548173240794
202789-VAR:
202789-50G-PW:

Certificates of Analysis (COA)

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Michael Schmidt et al.
Inorganic chemistry, 36(10), 2040-2043 (1997-05-07)
Maleic and phthalic acids are found to react with Be(OH)(2), generated in situ from BeSO(4)(aq) and Ba(OH)(2)(aq), in aqueous solution at pH 3.0 or 4.4, respectively (25 degrees C), to give solutions containing the complexes (H(2)O)(2)Be[(OOCCH)(2)] (1) and (H(2)O)(2)Be[(OOC)(2)C(6)H(4)] (3).
Andrew P Fontenot et al.
The Journal of clinical investigation, 110(10), 1473-1482 (2002-11-20)
Chronic beryllium disease (CBD) is caused by exposure to beryllium in the workplace, and it remains an important public health concern. Evidence suggests that CD4(+) T cells play a critical role in the development of this disease. Using intracellular cytokine
Richard T Sawyer et al.
Free radical biology & medicine, 38(7), 928-937 (2005-03-08)
Beryllium (Be), the etiologic agent of chronic beryllium disease, is a toxic metal that induces apoptosis in human alveolar macrophages. We tested the hypothesis that Be stimulates the formation of reactive oxygen species (ROS) which plays a role in Be-induced
P Joseph et al.
Molecular carcinogenesis, 32(1), 28-35 (2001-09-25)
Differential gene expression was studied to understand the potential molecular mechanism responsible for cell transformation and tumorigenesis induced by beryllium. Cell lines were derived from tumors developed in nude mice injected subcutaneously with BALB/c-3T3 cells morphologically transformed with beryllium sulfate.
S S Tinkle et al.
American journal of respiratory and critical care medicine, 156(6), 1884-1891 (1997-12-31)
Chronic beryllium disease (CBD) provides a model system in which to evaluate the antigen-stimulated, cell-mediated, immune response that leads to granulomatous lung disease. We hypothesized that beryllium salts would stimulate bronchoalveolar lavage (BAL) cell release of tumor necrosis factor-alpha (TNF-alpha)
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