Skip to Content
Merck
All Photos(4)

Key Documents

View All Documentation

Safety Information

201154

Sigma-Aldrich

Sodium fluoride

ACS reagent, ≥99%

Sign Into View Organizational & Contract Pricing

Select a Size

5 G
¥6,660
100 G
¥8,620
500 G
¥18,400

¥6,660

Estimated to ship onMarch 28, 2025

Request a Bulk Order
All Photos(4)

Select a Size

Change View
5 G
¥6,660
100 G
¥8,620
500 G
¥18,400

About This Item

Linear Formula:
NaF
CAS Number:
7681-49-4
Molecular Weight:
41.99
EC Number:
231-667-8
MDL number:
MFCD00003524
UNSPSC Code:
12352302
PubChem Substance ID:
329751974
NACRES:
NA.21
Assay:
≥99%
grade:
ACS reagent
form:
powder

¥6,660

Estimated to ship onMarch 28, 2025

Request a Bulk Order

grade

ACS reagent

Quality Level

200

Agency

suitable for EPA 300

vapor pressure

1.4 mmHg ( 0 °C)

Assay

≥99%

form

powder

impurities

≤0.01 meq/g Titr. base
≤0.02% insolubles
≤0.03 meq/g Titr. acid
≤0.1% sodium fluorosilicate

loss

≤0.3% loss on drying

mp

993 °C (lit.)

anion traces

chloride (Cl-): ≤0.005%
sulfate (SO42-): ≤0.03%
sulfite (SO32-): ≤0.005%

cation traces

Fe: ≤0.003%
K: ≤0.02%
heavy metals (as Pb): ≤0.003%

SMILES string

[F-].[Na+]

InChI

1S/FH.Na/h1H;/q;+1/p-1

InChI key

PUZPDOWCWNUUKD-UHFFFAOYSA-M

Looking for similar products? Visit Product Comparison Guide

General description

Sodium fluoride (NaF) is a metallic halide. It has been reported as dental caries preventive agent.[1] It is the most widely employed chemical preservative for the preservation of glucose in blood.[2] It has been reported to stabilize the hepatic microsomal glucose-6-P phosphohydrolase enzyme.[3]

Application

Sodium fluoride may be employed as a fluorination agent in the synthesis of aromatic and aliphatic fluorides.[4] It may be used to prepare the lysis buffer.[5]
Sodium fluoride may be used as a fluorinating agent for chlorine-containing compounds via halogen-exchange reaction.[4]
Starting material for solid state preparation of Na3MnF6 for further high pressure structural determination studies.[6]

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H301,H315,H319

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2

Supplementary Hazards

EUH032

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PDSCL

Deleterious substance

PRTR

Class I Designated Chemical Substances

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

201154-500G:4548173216744
201154-VAR:
201154-6X500G:
201154-BULK:
201154-5G:4548173216751
201154-100G:4548173216737

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKCW1585
MKCW1584
MKCV4470
MKCV1619
MKCS9939

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

A prospective, randomized clinical study on the effects of an amine fluoride/stannous fluoride toothpaste/mouthrinse on plaque, gingivitis and initial caries lesion development in orthodontic patients.
?gaard B, et al.
European Journal of Orthodontics, 28(1), 8-12 (2006)
The effect on human dental caries of weekly oral rinsing with a sodium fluoride mouthwash: a final report.
Horowitz HS, et al.
Archives of Oral Biology, 16(6), 609-616 (1971)
J G Drachman et al.
The Journal of biological chemistry, 270(10), 4979-4982 (1995-03-10)
c-Mpl is a member of the cytokine receptor superfamily, expressed primarily on hematopoietic cells. Recently, the c-Mpl ligand was cloned and found to have thrombopoietic activity. In this paper we report that ligand binding induced tyrosine phosphorylation in BaF3 cells
Effectiveness of sodium fluoride as a preservative of glucose in blood.
Chan AY, et al.
Clinical Chemistry, 35(2), 315-317 (1989)
A J Lange et al.
The Journal of biological chemistry, 261(1), 101-107 (1986-01-05)
Stabilization and inhibition of hepatic microsomal glucose-6-P phosphohydrolase (EC 3.1.3.9) by F- requires the presence of Al3+ ions. At millimolar concentrations, reagent grade NaF inhibited glucose-6-P hydrolysis and protected the enzyme against inactivation induced by heat in the presence of
View All Related Papers

Related Content

Environmental Methods Consumables Look Up Tool

This page is intended to make it easier to find the consumables you need based on the analytical method you’re using. Methods included on this page come from the EPA, Standard Methods and ASTM.

Questions

1–2 of 2 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service