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Safety Information

170852

Sigma-Aldrich

Hexyl nicotinate

97%

Synonym(s):

Nicotinic acid hexyl ester

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About This Item

Empirical Formula (Hill Notation):
C12H17NO2
CAS Number:
23597-82-2
Molecular Weight:
207.27
MDL number:
MFCD00023587

Assay

97%

SMILES string

CCCCCCOC(=O)c1cccnc1

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Precautionary Statements

P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

FSL

Group 4: Flammable liquids
Type 3 petroleums
Hazardous rank III
Water insoluble liquid

JAN Code

170852-100ML:
170852-BULK:
170852-25ML:

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Certificates of Analysis (COA)

Lot/Batch Number
10205KY
21999

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E Oestmann et al.
The British journal of dermatology, 128(2), 130-136 (1993-02-01)
This study assesses the variability of two non-invasive methods of measuring stratum corneum barrier function in vivo. Transepidermal water loss (TEWL), and the vascular response to hexyl nicotinate (HN) penetration as determined by laser-Doppler flowmetry, were measured in a group
K S Ryatt et al.
The British journal of dermatology, 119(3), 307-312 (1988-09-01)
The effect of short duration occlusion on skin penetration and stratum corneum water content was studied in vivo in eight human subjects. Percutaneous absorption of hexyl nicotinate was monitored non-invasively by laser Doppler velocimetry (LDV) following each of three randomly
Slaheddine Marrakchi et al.
Contact dermatitis, 55(1), 15-19 (2006-07-18)
Variation in human skin reactivity to various irritants in association with age and body region has been reported. Hexyl nicotinate (HN), a lipophilic nicotinate ester, was used to induce nonimmunologic contact urticaria in human volunteers of 2 age groups: 10
A P Lavrijsen et al.
The British journal of dermatology, 129(5), 547-553 (1993-11-01)
In this study, we characterized the stratum corneum barrier function in 39 patients with various keratinization disorders (autosomal dominant ichthyosis vulgaris [ADI] [n = 7], X-linked recessive ichthyosis [XRI] [n = 6], autosomal recessive congenital ichthyosis [CI] [n = 10]
L R Barclay et al.
Lipids, 32(3), 237-245 (1997-03-01)
The monoazaaromatics, pyridine (1), hexyl nicotinate (2), and quinoline (3) and diazaaromatics, pyrimidine (4) and purine (5), readily act as photo-initiators for the peroxidation of methyl linoleate in 0.50 M SDS at 37 degrees C giving free radical chain oxidations
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