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127442

Sigma-Aldrich

Aminomethanesulfonic acid

97%

Synonym(s):

(Aminomethyl)sulfonic acid, 1-Aminomethanesulfonic acid, Aminomethanesulfonic acid, Aminomethanesulphonic acid, aminomethylsulfonic acid

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About This Item

Linear Formula:
NH2CH2SO3H
CAS Number:
13881-91-9
Molecular Weight:
111.12
Beilstein:
1811756
EC Number:
237-649-6
MDL number:
MFCD00008124
UNSPSC Code:
12352106
PubChem Substance ID:
24847780
NACRES:
NA.22

Assay

97%

mp

184 °C (dec.) (lit.)

SMILES string

NCS(O)(=O)=O

InChI

1S/CH5NO3S/c2-1-6(3,4)5/h1-2H2,(H,3,4,5)

InChI key

OBESRABRARNZJB-UHFFFAOYSA-N

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Application

Aminomethanesulfonic acid can be used as a reactant to synthesize: 1-Sulfomethyltetrazole-5-thiol disodium salts, which are useful key intermediates for the preparation of cefonicid sodium. Tridentate N-(2-hydroxybenzyl)aminomethane sulfonic acid Schiff-base ligand by reacting with salicylaldehyde.
It can also be used to functionalize the surface of single-walled carbon nanotubes (SWCNT) or porous metal-organic frameworks (MOF) to introduce the sulfonic acid functional groups for the preparation of nanocomposites.

Pictograms

Corrosion
GHS05

Signal Word

Danger

Hazard Statements

H314

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

127442-50G:
127442-BULK:
127442-VAR:
127442-10G:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Synthesis of 1-sulfomethyltetrazole-5-thiol disodium salts
Ling Zhang, et al.
Speciality Petrochemicals (2011)
Nigel G Ternan et al.
FEMS microbiology letters, 207(1), 49-53 (2002-03-12)
Chromohalobacter marismortui VH1 was screened for its ability to utilise organosulfonate compounds at a range of NaCl concentrations. Only aminomethane sulfonate, of seven sulfonates tested, was utilised. Length of lag phase during growth on aminomethane sulfonate, as either nitrogen and/or
J B Lombardini
European journal of pharmacology, 110(3), 385-387 (1985-04-16)
It is well known that taurine stimulates ATP-dependent calcium ion uptake at low calcium ion concentrations. However, aminomethanesulfonic acid, the lower homologue of taurine, inhibits calcium ion uptake under the same experimental conditions. The higher homologue of taurine, 3-aminopropanesulfonic acid
Copper (II) complexes of Schiff-base and reduced Schiff-base ligands: Influence of weakly coordinating sulfonate groups on the structure and oxidation of 3, 5-DTBC
Sreenivasulu B, et al.
European Journal of Inorganic Chemistry, 2005(22), 4635-4645 (2005)
W S Lewis et al.
The Journal of biological chemistry, 266(31), 20823-20827 (1991-11-05)
The composition and structural aspects of the amino and carboxylic acid groups required for incorporation into peptides by transpeptidation and inhibition of hydrolysis in carboxypeptidase Y-catalyzed reactions were studied. Separation of these two groups by even one carbon prevents incorporation
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