An unexpected silver triflate catalyzed reaction of 2-alkynylbenzaldehyde with 2-isocyanoacetate.

An unexpected silver triflate catalyzed reaction of 2-alkynylbenzaldehyde with 2-isocyanoacetate.

Organic letters (2012-05-24)

Danqing Zheng, Shaoyu Li, Jie Wu

ABSTRACT

An unexpected silver triflate catalyzed reaction of 2-alkynylbenzaldehyde with 2-isocyanoacetate provides an efficient route for the generation of isoquinolines. The reaction proceeds smoothly in air under mild conditions with high efficiency.

MATERIALI

N° Catalogo

Marchio

Descrizione del prodotto

290068

Sigma-Aldrich

Zinc trifluoromethanesulfonate, 98%

347817

Sigma-Aldrich

Trifluoromethanesulfonic acid, ReagentPlus^®, ≥99%

176435

Sigma-Aldrich

Silver trifluoromethanesulfonate, ≥99%

515884

Sigma-Aldrich

Aluminum trifluoromethanesulfonate, 99.9% trace metals basis

481548

Sigma-Aldrich

Lithium trifluoromethanesulfonate, 99.995% trace metals basis

483346

Sigma-Aldrich

Silver trifluoromethanesulfonate, ≥99.95% trace metals basis

430609

Sigma-Aldrich

Lanthanum(III) trifluoromethanesulfonate, 99.999% trace metals basis

282669

Sigma-Aldrich

Lithium trifluoromethanesulfonate, 96%

158534

Sigma-Aldrich

Trifluoromethanesulfonic acid, reagent grade, 98%

85325

Sigma-Aldrich

Silver trifluoromethanesulfonate, purum, ≥98.0% (Ag)