1336205

Ifosfamide

United States Pharmacopeia (USP) Reference Standard

• Sinonimo/i: Ifex, N,3-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine-2-oxide
• Formula empirica (notazione di Hill): C₇H₁₅Cl₂N₂O₂P
• Numero CAS: 3778-73-2
• Peso molecolare: 261.09
• NACRES: NA.24
• PubChem Substance ID: 329750149
• UNSPSC Code: 41116107
• MDL number: MFCD00057374

Proprietà

• grade: pharmaceutical primary standard
• agency: USP
• API family: ifosfamide
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule); pharmaceutical
• format: neat
• storage temp.: 2-8°C
• SMILES string: ClCCNP1(=O)OCCCN1CCCl
• InChI: 1S/C7H15Cl2N2O2P/c8-2-4-10-14(12)11(6-3-9)5-1-7-13-14/h1-7H2,(H,10,12)
• InChI key: HOMGKSMUEGBAAB-UHFFFAOYSA-N

Descrizione

General description

Find answers to frequently asked questions on USP products in USP FAQs.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Biochem/physiol Actions

Ifosfamide is a nitrogen mustard compound that is a structural isomer of cyclophosphamide. Ifosfamide is a prodrug that must be transformed by cytochrome P450 to the biologically active component. It is used as an antineoplastic agent in cancer chemotherapy, but ifosfamide is more likely to cause renal toxicity than cyclophosphamide.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Informazioni sulla sicurezza

• Pittogrammi: GHS06,GHS08
• Parola di avvertenza: Danger
• Codici di pericolo: H301,H319,H340,H350,H360FD
• Avvertenze di sicurezza: P202 - P264 - P280 - P301 + P310 + P330 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 3 Oral - Carc. 1B - Eye Irrit. 2 - Muta. 1B - Repr. 1B
• Classe di stoccaggio: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Punto di infiammabilità (°F): Not applicable
• Punto di infiammabilità (°C): Not applicable