V5390

VU0029251

≥98% (HPLC), powder

• Sinonimo/i: 6,7-Dihydro-2-(methylthio)-5H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-amine
• Formula empirica (notazione di Hill): C₁₀H₁₁N₃S₂
• Peso molecolare: 237.34
• Numero MDL: MFCD00698485
• Codice UNSPSC: 12352200
• ID PubChem: 329829058
• NACRES: NA.77

Proprietà

• Saggio: ≥98% (HPLC)
• Forma fisica: powder
• Colore: white to tan
• Solubilità: DMSO: ≥11 mg/mL
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: CSc1nc(N)c2c3CCCc3sc2n1
• InChI: 1S/C10H11N3S2/c1-14-10-12-8(11)7-5-3-2-4-6(5)15-9(7)13-10/h2-4H2,1H3,(H2,11,12,13); WDDBZCKBRCTSOZ-UHFFFAOYSA-N

Descrizione

Azioni biochim/fisiol

VU0029251 is the first example of a partial mGluR5 partial antagonist that is not based on the MPEP scaffold. The compound displays a maximum inhibition of 50% activity, and cannot completely displace [3H] MPEP, suggesting that competition for MPEP is also allosteric, involving a unique site.

Caratteristiche e vantaggi

This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 13 - Non Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable