Unfortunately, solution stability studies of this product have not been performed. However, other sources state that this chemical is stable when stored at -20°C for up to 3 months. Avoid repeated freeze/thaw cycles.
Please see the link below to review the product datasheet:
https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/132/566/t4680pis.pdf
T4680
Terazosin hydrochloride
≥98% (TLC), α1-adrenoceptor antagonist, powder
Sinonimo/i:
1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]piperazine hydrochloride
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Cambia visualizzazione
| A voi/SKU | Disponibilità | Prezzo |
|---|---|---|
50 mg | Per informazioni sulla disponibilità, contatta il Servizio Clienti. | 163,00 € 138,55 € |
250 mg | Per informazioni sulla disponibilità, contatta il Servizio Clienti. | 707,00 € 600,95 € |
Informazioni su questo articolo
Formula empirica (notazione di Hill):
C19H25N5O4 · HCl
Numero CAS:
Peso molecolare:
423.89
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (TLC)
Form:
powder
138,55 €
Prezzo di listino163,00 €Risparmia il 15%Promozione valida solo online
Per informazioni sulla disponibilità, contatta il Servizio Clienti.
Servizio Tecnico
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Permettici di aiutartiNome del prodotto
Terazosin hydrochloride, ≥98% (TLC), powder
Quality Segment
assay
≥98% (TLC)
form
powder
color
white to off-white
solubility
H2O: soluble 19.60-20.40 mg/mL, clear, colorless to faintly yellow, methanol: 20 mg/mL, clear, colorless, ethanol: 4 mg/mL
originator
Abbott
SMILES string
Cl[H].COc1cc2nc(nc(N)c2cc1OC)N3CCN(CC3)C(=O)C4CCCO4
InChI
1S/C19H25N5O4.ClH/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14;/h10-11,14H,3-9H2,1-2H3,(H2,20,21,22);1H
InChI key
IWSWDOUXSCRCKW-UHFFFAOYSA-N
Gene Information
human ... ADRA1A(148), ADRA1B(147), ADRA1D(146)
General description
Terazosin hydrochloride is used to treat hypertension and benign prostatic hyperplasia (BPH). It is metabolised in the liver. It might be associated with dizziness, headache and asthenia. Terazosin hydrochloride is linked to acute generalized exanthematous pustulosis.
Application
Terazosin hydrochloride has been used for orthogonality and similarity analysis using reversed-phase chromatographic studies5. Furthermore, terazosin has also been used for the evaluation of chemometric techniques to determine orthogonality and similarity in chromatographic methods6.
Biochem/physiol Actions
α1-adrenoceptor antagonist.
Features and Benefits
This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
Preparation Note
Terazosin hydrochloride is soluble in water at 19.60 - 20.40 mg/ml and yields a clear, colorless to faint yellow solution. It is also soluble in ethanol at 4 mg/ml. Furthermore, the product is soluble in methanol at 20 mg/ml, with heat as needed, and yields a clear, colorless solution.
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Questo articolo | |||
|---|---|---|---|
| form powder | form - | form - | form powder |
| assay ≥98% (TLC) | assay - | assay - | assay ≥99.0% (HPLC) |
| Quality Level 200 | Quality Level 300 | Quality Level - | Quality Level 100 |
| solubility H2O: soluble 19.60-20.40 mg/mL, clear, colorless to faintly yellow, ethanol: 4 mg/mL, methanol: 20 mg/mL, clear, colorless | solubility - | solubility - | solubility H2O: 0.5 mg/mL, methanol: 6 mg/mL, dilute aqueous acid: insoluble |
| color white to off-white | color - | color - | color - |
| Gene Information human ... ADRA1A(148), ADRA1B(147), ADRA1D(146) | Gene Information human ... ADRA1A(148), ADRA1B(147), ADRA1D(146) | Gene Information human ... ADRA1A(148), ADRA1B(147), ADRA1D(146) | Gene Information human ... ADRA1A(148), ADRA1B(147), ADRA1D(146) |
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
Classe di stoccaggio
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Can this product be frozen in saline solution and thawed for later use? For how long is the product stable in solution or should it be made fresh prior to use?
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