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Merck
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Documenti fondamentali

SRP6333

Sigma-Aldrich

CD74 human

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

Sinonimo/i:

DHLAG, HLA class II histocompatibility antigen gamma chain isoform b, HLADG, Ia-GAMMA

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About This Item

Codice UNSPSC:
12352200
NACRES:
NA.32

Origine biologica

human

Ricombinante

expressed in E. coli

Saggio

≥90% (SDS-PAGE)

Stato

liquid

PM

20.6 kDa (183 aa, 73-232 aa + His tag)

Confezionamento

pkg of 100 μg

Concentrazione

0.5 mg/mL

Impurezze

<1 EU/μg endotoxin (LAL test)

N° accesso UniProt

P04233

Condizioni di spedizione

dry ice

Temperatura di conservazione

−70°C

Informazioni sul gene

human ... CD74(972)

Descrizione generale

HLA class II histocompatibility antigen gamma chain isoform b, also known as CD74, is a transmembrane protein which, on antigen presenting cells, is the invariant chain that chaperones MHC class II dimers from the endoplasmic reticulum to the cell surface. CD74 is expressed by cells of both T lymphocyte and B lymphocyte lineages. It is upregulated in several cancers and is also expressed by nonimmune cells during inflammation. Recombinant human CD74 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Stato fisico

0.5 mg/mL in 20 mM Tris-HCl buffer (pH 8.0) containing 0.1 M NaCl, 1 mM DTT and 30% glycerol.

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H319

Classi di pericolo

Eye Irrit. 2

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number

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