SRP6206

sCD22 human

recombinant, expressed in E. coli, ≥98% (SDS-PAGE)

• Sinonimo/i: B Lymphocyte cell adhesion molecule, BL-CAM, Leu-14, Siglec-2
• Codice UNSPSC: 12352200
• NACRES: NA.32

Proprietà

• Origine biologica: human
• Ricombinante: expressed in E. coli
• Saggio: ≥98% (SDS-PAGE)
• Forma fisica: lyophilized powder
• PM: ~75 kDa
• Confezionamento: pkg of 10 μg; pkg of 50 μg
• Impurezze: <1 EU/μg endotoxin (LAL test)
• N° accesso UniProt: P20273
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• Informazioni sul gene: human ... CD22(933)

Descrizione

Descrizione generale

CD22 is a B-lineage restricted 135 kDa glycoprotein whose cell surface expression is limited to resting and activated B lymphocytes. The physiological role of CD22 is still unknown. Targeted disruption of CD22 in mice results in a reduced level of surface IgM on peripheral B cells suggesting a role for CD22 in limiting antigen receptor signaling. CD22 is a member of the Ig gene superfamily that uniquely binds a sialic acid-dependent ligand. Recombinant human CD22 is a soluble 75.0 kDa protein which corresponds to the extracellular domain of CD22.

Stato fisico

Sterile filtered through a 0.2 micron filter. Lyophilized from 1X PBS, pH 7.2.

Ricostituzione

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 13 - Non Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable