SRP6064
UCHL1 human
recombinant, expressed in E. coli, ≥95% (SDS-PAGE)
Sinonimo/i:
PARK5, PGP9.5, UCHL1, Ubiquitin carboxyl-terminal esterase L1, Uch-L1
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About This Item
Codice UNSPSC:
12352200
Prodotti consigliati
Origine biologica
human
Ricombinante
expressed in E. coli
Saggio
≥95% (SDS-PAGE)
Stato
liquid
PM
24.8 kDa (223 aa)
Confezionamento
pkg of 100 μg
N° accesso NCBI
Condizioni di spedizione
dry ice
Temperatura di conservazione
−70°C
Informazioni sul gene
human ... UCHL1(7345)
Descrizione generale
PGP9.5/UCH-L1 is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. PGP9.5 is a component of the ubiquitin system, which has a fundamental role in regulating various biological activities. PGP9.5 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson′s disease susceptibility. Recombinant PGP9.5 protein was expressed in E.coli and purified by using conventional chromatography techniques.
Stato fisico
1 mg/mL solution in In 20 mM Tris-HCl buffer (pH 8.0) containing 2 mM EDTA.
Nota sulla preparazione
Centrifuge the vial prior to opening.
Altre note
MQLKPMEINP EMLNKVLSRL GVAGQWRFVD VLGLEEESLG SVPAPACALL LLFPLTAQHE NFRKKQIEEL KGQEVSPKVY FMKQTIGNSC GTIGLIHAVA NNQDKLGFED GSVLKQFLSE TEKMSPEDRA KCFEKNEAIQ AAHDAVAQEG QCRVDDKVNF HFILFNNVDG HLYELDGRMP FPVNHGASSE DTLLKDAAKV CREFTEREQG EVRFSAVALC KAA
Codice della classe di stoccaggio
12 - Non Combustible Liquids
Classe di pericolosità dell'acqua (WGK)
WGK 1
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Certificati d'analisi (COA)
Lot/Batch Number
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Ewa Matuszczak et al.
Advances in medical sciences, 62(1), 83-86 (2017-02-15)
The study aims to determinate concentrations of ubiquitin C-terminal hydrolase 1 (UCHL1), which hydrolyzes amino acids from ubiquitin and cleave di-ubiquitins, in serum of children after thermal injury. 42 children scalded by hot water, managed at the Department of Pediatric
Vikram Puvenna et al.
PloS one, 9(5), e96296-e96296 (2014-05-09)
The impact of sub-concussive head hits (sub-CHIs) has been recently investigated in American football players, a population at risk for varying degrees of post-traumatic sequelae. Results show how sub-CHIs in athletes translate in serum as the appearance of reporters of
Roshan Kumar et al.
Scientific reports, 7, 44558-44558 (2017-03-17)
Ubiquitin C-terminal Hydrolase-1 (UCHL1) is a deubiquitinating enzyme, which plays a key role in Parkinson's disease (PD). It is one of the most important proteins, which constitute Lewy body in PD patient. However, how this well folded highly soluble protein
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