SRP6036

CD-14 from mouse

recombinant, expressed in CHO cells, 90-95% (SDS-PAGE)

• Sinonimo/i: CD14, Cluster of differentiation 14
• Codice UNSPSC: 12352200
• NACRES: NA.32

Proprietà

• Origine biologica: mouse
• Ricombinante: expressed in CHO cells
• Saggio: 90-95% (SDS-PAGE)
• Forma fisica: lyophilized
• PM: 50.0 kDa
• Confezionamento: pkg of 10 μg
• Impurezze: Endotoxin, tested
• N° accesso NCBI: P10810
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• Informazioni sul gene: mouse ... CD14(12475)

Descrizione

Descrizione generale

CD14 acts as a receptor for endotoxin (LPS), is expressed strongly on monocy¬tes, macrophages and weekly at surface of neutrophiles. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor LPS-LBP (lipopolysaccharide binding protein)-complexes. Furthermore CD14 is present in a soluble form in human serum, urine and other body fluids, acts at physiological concentrations as LPS agonist and has at higher concentrations an antagonizing effect in cell activation. The myeloid differentiation antigen CD14 acts as the major receptor for bacterial LPS. The dominant form of the recombinant wild type CD14 is the 50 kDa protein. This is a His-tagged protein.

Stato fisico

Lyophilized from a concentrated protein solution (1 mg/ml) containing PBS, pH 7.2

Ricostituzione

Centrifuge the vial prior to opening. Reconstitute in 10 μl of ultra-pure distilled water. This solution can then be diluted into other aqueous buffers.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 13 - Non Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable