SML2946

Biotin-aniline

≥98% (HPLC)

• Sinonimo/i: (3aS,4S,6aR)-N-[2-(4-Aminophenyl)ethyl]hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide, Btn-An, N-(4-Aminophenethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide, N-(4-Aminophenethyl)biotinamide
• Formula empirica (notazione di Hill): C₁₈H₂₆N₄O₂S
• Numero CAS: 769933-15-5
• Peso molecolare: 362.49
• Codice UNSPSC: 12352200
• NACRES: NA.77

Proprietà

• Livello qualitativo: 100
• Saggio: ≥98% (HPLC)
• Stato: powder
• Colore: white to beige
• Solubilità: DMSO: 2 mg/mL, clear
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: O=C(CCCC[C@@H]1SC[C@]([H])(N2)[C@@]1(NC2=O)[H])NCCC3=CC=C(C=C3)N
• InChI: 1S/C18H26N4O2S/c19-13-7-5-12(6-8-13)9-10-20-16(23)4-2-1-3-15-17-14(11-25-15)21-18(24)22-17/h5-8,14-15,17H,1-4,9-11,19H2,(H,20,23)(H2,21,22,24)/t14-,15-,17-/m0/s1; AHRRICHWBPPWDZ-ZOBUZTSGSA-N

Descrizione

Azioni biochim/fisiol

A superior substrate than biotinyl tyramide (biotin-phenol; BP) for APEX2-mediated proximity-labeling of RNA.

Biotin-aniline (Btn-An) is a superior substrate than biotinyl tyramide (biotin-phenol; BP) for APEX2-mediated proximity labeling of RNA (∼25-fold higher by dot blot with 0.5 mM substrate and 0.4-10 μg RNA/dot). Btn-An specifically labels mitochondrial, but not cytoplasmic, mRNAs in live HEK293T stable line expressesing APEX2 in the mitochondrial matrix (mito-APEX2).

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable