SML2941

Maribavir

≥98% (HPLC)

• Sinonimo/i: (2S,3S,4R,5S)-2-(5,6-Dichloro-2-(isopropylamino)-1H-benzo[d]imidazol-1-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol, 1263W94, Benzimidavir, VP-41263
• Formula empirica (notazione di Hill): C₁₅H₁₉Cl₂N₃O₄
• Numero CAS: 176161-24-3
• Peso molecolare: 376.24
• NACRES: NA.77
• UNSPSC Code: 12352200
• Assay: ≥98% (HPLC)
• Form: powder

Proprietà

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: −20°C
• SMILES string: CC(NC1=NC2=CC(Cl)=C(Cl)C=C2N1[C@@H]3[C@@H](O)[C@@H](O)[C@H](CO)O3)C
• InChI: 1S/C15H19Cl2N3O4/c1-6(2)18-15-19-9-3-7(16)8(17)4-10(9)20(15)14-13(23)12(22)11(5-21)24-14/h3-4,6,11-14,21-23H,5H2,1-2H3,(H,18,19)/t11-,12-,13-,14-/m0/s1
• InChI key: KJFBVJALEQWJBS-XUXIUFHCSA-N

Descrizione

Biochem/physiol Actions

Maribavir is an orally available antiviral agent under development for treatment and prevention of human cytomegalovirus (HCMV) infection. Maribavir is a potent and selective ATP-competitive inhibitor of HCMV protein kinase pUL97 that blocks viral replication.

potent and selective ATP-competitive inhibitor of HCMV protein kinase pUL97; orally available antiviral agent

Informazioni sulla sicurezza

• Che succede?: WGK 3
• Pittogrammi: GHS07
• Parola di avvertenza: Warning
• Codici di pericolo: H302
• Avvertenze di sicurezza: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Classe di stoccaggio: 11 - Combustible Solids
• Punto di infiammabilità (°F): Not applicable
• Punto di infiammabilità (°C): Not applicable