SMB00089

Dehydroabietic acid

≥90% (LC/MS-ELSD)

• Sinonimo/i: Abieta-8,11,13-trien-18-oic acid, Dehydroabietate
• Formula empirica (notazione di Hill): C₂₀H₂₈O₂
• Numero CAS: 1740-19-8
• Peso molecolare: 300.44
• Numero CE: 217-102-8
• Numero MDL: MFCD09839012
• Codice UNSPSC: 12352205
• ID PubChem: 329824767
• NACRES: NA.25

Proprietà

• Saggio: ≥90% (LC/MS-ELSD)
• Forma fisica: solid
• applicazioni: metabolomics; vitamins, nutraceuticals, and natural products
• Temperatura di conservazione: −20°C
• Stringa SMILE: CC(C)c1ccc2c(CC[C@H]3[C@@](C)(CCC[C@]23C)C(O)=O)c1
• InChI: 1S/C20H28O2/c1-13(2)14-6-8-16-15(12-14)7-9-17-19(16,3)10-5-11-20(17,4)18(21)22/h6,8,12-13,17H,5,7,9-11H2,1-4H3,(H,21,22)/t17-,19-,20-/m1/s1; NFWKVWVWBFBAOV-MISYRCLQSA-N

Descrizione

Descrizione generale

Dehydroabietic acid (DHA or DAA) is a bioactive phytochemical, diterpenoid found in various Pinus species. It is a resin acid and a derivative of abietic acid (AA).

Applicazioni

Dehydroabietic acid has been used as a reference standard:

• to study the aging process of Pinus resins using Fourier-transform infrared spectroscopy (FTIR)
• to study the composition changes in Pinus genus with aging using Raman spectroscopy complemented with infrared spectroscopy
• to estimate resistance against biotic stress as proxy in chemical defenses in Pinus halepensis

Azioni biochim/fisiol

Dehydroabietic acid (DHA) exerts various biological activities such as anti-cancer, anti-aging, antimicrobial, antiulcer, gastroprotective, and cytotoxic activities. It is a potent anti-inflammatory agent and a dual activator of peroxisome proliferator-activated receptors alpha and gamma (PPAR α/γ). DHA has an anti-aging effect and a sirtuin 1 (SIRT1) activating compound. It has antibacterial properties against multidrug-resistant strains. dehydroabietic acid and its derivatives have gastroprotective and cytotoxic effects.

Informazioni sulla sicurezza

• Pittogrammi: GHS06,GHS09
• Avvertenze: Danger
• Indicazioni di pericolo: H301,H410
• Consigli di prudenza: P273 - P301 + P310 + P330
• Classi di pericolo: Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1
• Codice della classe di stoccaggio: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable