SAE0219

Mucin Degradation Enzyme

for preparative digestions, powder

Proprietà

• Livello qualitativo: 200
• Forma fisica: powder
• Durata: 2 yr (retest)
• Condizioni di stoccaggio: protect from light
• Condizioni di spedizione: dry ice
• Temperatura di conservazione: -10 to -25°C

Descrizione

Descrizione generale

Mucin Degradation Enzyme is a metalloprotease useful for digesting heavily O-glycosylated mucin proteins. This product is made for preparative scale digestions of viscous material that is dense with mucin-type glycoproteins.

Applicazioni

For use as a sample preparation tool in research and discovery. Used for proteolytic degradation of mucin-dense tissues to allow for downstream processing.

Azioni biochim/fisiol

The Mucin Degradation enzyme is a mutated form of a protease that specifically recognizes densely glycosylated mucins and mucin-domains, and proteolytically cleaves the peptide backbone. In nature this presumably enhances the virulence of the pathogenic microbe, but in the laboratory is a useful way of accessing molecular structures in tissues normally shielded by mucins.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 13 - Non Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable