SAB5702738

Anti-LIN28A Antibody, clone 2S1I10, Rabbit Monoclonal

• Sinonimo/i: CSDD1, LIN-28, LIN28, ZCCHC1, lin-28A
• Codice UNSPSC: 12352203
• NACRES: NA.46

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Materiali: colorless
• Clone: 2S1I10, monoclonal
• Forma fisica: liquid
• PM: 26 kDa
• Reattività contro le specie: human, rat, rat
• Concentrazione: 0.70 mg/mL
• tecniche: immunofluorescence: 1:50 - 1:200; western blot: 1:10000 - 1:20000
• Colore: colorless
• Isotipo: IgG
• Sequenza immunogenica: MGSVSNQQFAGGCAKAAEEAPEEAPEDAARAADEPQLLHGAGICKWFNVRMGFGFLSMTARAGVALDPPVDVFVHQSKLHMEGFRSLKEGEAVEFTFKKS
• N° accesso UniProt: Q9H9Z2
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... LIN28A(79727)

Descrizione

Descrizione generale

This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues. [provided by RefSeq, Sep 2015]

Immunogeno

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human LIN28A (Q9H9Z2).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Applicazioni

WB, IF/ICC

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1