SAB4702047

Monoclonal Anti-CD81 APC-Cyanine7 produced in mouse

• Sinonimo/i: CVID6, S5.7, TAPA1, TSPAN28
• Codice UNSPSC: 12352203

Proprietà

• Coniugato: APC-Cy7 conjugate
• Livello qualitativo: 100
• Tipo di anticorpo: primary antibodies
• Clone: M38, monoclonal
• Forma fisica: buffered aqueous solution
• Reattività contro le specie: ( Human), rabbit, ( Cat)
• tecniche: flow cytometry: suitable
• Isotipo: IgG1
• N° accesso UniProt: P60033
• Temperatura di conservazione: 2-8°C
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... CD81(975)

Descrizione

Descrizione generale

CD81 (TAPA-1), a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T and other cells, e.g. in muscles CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus.

Specificità

The antibody M38 reacts with an extracellular epitope of CD81, a 25 kDa member of the tetraspanin family, expressed on majority of cells.

Immunogeno

MOLT-4 (human T-ALL cell line)

Stato fisico

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Nota sulla preparazione

Purified antibody is conjugated with activated tandem dye of allophycocyanin-cyanine 7 (APC-Cy7) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Stoccaggio e stabilità

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Altre note

The antibody solution should be gently mixed before use.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable