SAB4702001

Monoclonal Anti-CD34 PerCP produced in mouse

• Codice UNSPSC: 12352203

Proprietà

• Coniugato: Peridinin-Chlorophyll-Protein Complex conjugate
• Livello qualitativo: 100
• Tipo di anticorpo: primary antibodies
• Clone: 581, monoclonal
• Forma fisica: buffered aqueous solution
• Reattività contro le specie: ( Human), (Non-human primates)
• tecniche: flow cytometry: suitable
• Isotipo: IgG1κ
• N° accesso UniProt: P28906
• Temperatura di conservazione: 2-8°C
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... CD34(947)

Descrizione

Descrizione generale

CD34 is a highly glycosylated monomeric 111-115 kDa surface protein, which is present on many stem cell populations. It is a well established stem cell marker, though its expression on human hematopoietic stem cells is reversible. CD34 probably serves as a surface receptor that undergoes receptor-mediated endocytosis and regulates adhesion, differentiation and proliferation of hematopoietic stem cells and other progenitors. CD34 expression is likely to represent a specific state of hematopoietic development that may have altered adhering properties with expanding and differentiating capabilities in both in vitro and in vivo conditions.

Specificità

The mouse monoclonal antibody 581 reacts with an extracellular epitope of CD34, a 110-115 kDa monomeric transmembrane phosphoglycoprotein expressed on hematopoietic progenitors cells and on the most pluripotential stem cells; it is gradually lost on progenitor cells. The antibody recognizes the class III CD34 epitope resistant to neuraminidase, chymopapain and glycoprotease.

Stato fisico

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Nota sulla preparazione

Purified antibody is conjugated with activated Peridinin-Chlorophyll Protein (PerCP) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Stoccaggio e stabilità

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Altre note

The antibody solution should be gently mixed before use.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable