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Documenti fondamentali

SAB4700552

Sigma-Aldrich

Monoclonal Anti-Cd3e antibody produced in hamster

clone 145-2C11, purified immunoglobulin, buffered aqueous solution

Sinonimo/i:

Anti-CD3

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About This Item

Codice UNSPSC:
12352203
NACRES:
NA.41

Origine biologica

hamster

Coniugato

unconjugated

Forma dell’anticorpo

purified immunoglobulin

Tipo di anticorpo

primary antibodies

Clone

145-2C11, monoclonal

Stato

buffered aqueous solution

Reattività contro le specie

mouse

Concentrazione

1 mg/mL

tecniche

flow cytometry: suitable

Isotipo

IgG

N° accesso NCBI

N° accesso UniProt

Condizioni di spedizione

wet ice

Temperatura di conservazione

2-8°C

Informazioni sul gene

mouse ... Cd3e(12501)

Descrizione generale

The hamster monoclonal antibody 145-2C11 reacts with mouse CD3 (epsilon subunit). This antibody is commonly used as a phenotypic marker for mouse T cells.

Immunogeno

Mouse BM10-37 cytotoxic T lymphocytes

Applicazioni

The reagent is designed for Flow Cytometry analysis using 1-2 μg reagent / 1e6 cells in a suspension.

Caratteristiche e vantaggi

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Stato fisico

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

12 - Non Combustible Liquids

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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Susanne M A Lens et al.
Molecular and cellular biology, 22(15), 5419-5433 (2002-07-09)
The caspase 8 inhibitor c-FLIP(L) can act in vitro as a molecular switch between cell death and growth signals transmitted by the death receptor Fas (CD95). To elucidate its function in vivo, transgenic mice were generated that overexpress c-FLIP(L) in
Lisa A Pitcher et al.
European journal of immunology, 35(12), 3643-3654 (2005-11-01)
T cell receptor (TCR) signal transduction is mediated by the immunoreceptor tyrosine-based activation motifs (ITAM). The ten ITAM in the TCR complex are distributed in two distinct signaling modules termed TCR zetazeta and CD3 gammaepsilon/deltaepsilon. To delineate the specific role
Qizhi Tang et al.
Journal of immunology (Baltimore, Md. : 1950), 168(9), 4480-4487 (2002-04-24)
FcR nonbinding anti-CD3 epsilon mAbs elicit partial TCR signaling that leads to T cell unresponsiveness and tolerance in vivo. In this study, the membrane-proximal events that promote T cell inactivation by FcR nonbinding anti-CD3 mAbs were examined. In the context
Lingqiao Zhu et al.
Journal of immunology (Baltimore, Md. : 1950), 191(2), 737-744 (2013-06-19)
MHC class II-expressing thymocytes can efficiently mediate positive selection of CD4 T cells in mice. Thymocyte-selected CD4 (T-CD4) T cells have an innate-like phenotype similar to invariant NKT cells. To investigate the development and function of T-CD4 T cells in-depth
Joshua C Cyktor et al.
Infection and immunity, 81(4), 1090-1099 (2013-01-24)
The expression of T cell differentiation markers is known to increase during Mycobacterium tuberculosis infection, and yet the biological role of such markers remains unclear. We examined the requirement of the T cell differentiation marker killer cell lectin-like receptor G1

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