SAB4503712

Anti-GAB2 antibody produced in rabbit

affinity isolated antibody

• Sinonimo/i: GRB2-associated binder 2, GRB2-associated-binding protein 2, Growth factor receptor bound protein 2-associated protein 2, KIAA0571, pp100
• Numero MDL: MFCD02686157
• Codice UNSPSC: 12352203

Proprietà

• Origine biologica: rabbit
• Coniugato: unconjugated
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Stato: buffered aqueous solution
• PM: antigen 74 kDa
• Reattività contro le specie: rat, human, mouse
• Concentrazione: ~1 mg/mL
• tecniche: ELISA: 1:40000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• N° accesso NCBI: Q9UQC2
• N° accesso UniProt: Q9UQC2
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• Informazioni sul gene: human ... GAB2(9846)

Descrizione

Descrizione generale

Anti-GAB2 Antibody detects endogenous levels of total GAB2 protein.

GAB2 (GRB2 associated binding protein 2), a mammalian homolog of GAB1 is a member of the family of insulin receptor substrate 1-like multi-substrate proteins. It is located on human chromosome 11q14.

Immunogeno

The antiserum was produced against synthesized peptide derived from human Gab2.

Immunogen Range: 125-174

Azioni biochim/fisiol

GAB2 (GRB2 associated binding protein 2) plays a major role in proliferation, survival and differentiation. It induces the multiplication of cells by initiating the extracellular signal-regulated kinase (ERK) signaling pathway in hepatocellular carcinoma.

Caratteristiche e vantaggi

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Stato fisico

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): nwg
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable