Passa al contenuto
Merck
Tutte le immagini(2)

Documenti fondamentali

SAB4502917

Sigma-Aldrich

Anti-TP53INP2 antibody produced in rabbit

affinity isolated antibody

Sinonimo/i:

PIG-U, p53-inducible protein U

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
Tutte le immagini(2)

About This Item

Codice UNSPSC:
12352203
NACRES:
NA.41

Origine biologica

rabbit

Livello qualitativo

100

Coniugato

unconjugated

Forma dell’anticorpo

affinity isolated antibody

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Stato

buffered aqueous solution

PM

antigen 23 kDa

Reattività contro le specie

human, rat, mouse

Concentrazione

~1 mg/mL

tecniche

ELISA: 1:10000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100

N° accesso NCBI

Q8CFU8

Condizioni di spedizione

wet ice

Temperatura di conservazione

−20°C

Informazioni sul gene

human ... TP53INP2(58476)
mouse ... T53I2(68728)

Categorie correlate

Descrizione generale

Anti-TP53INP2 Antibody detects endogenous levels of total TP53INP2 protein.
TP53INP2/DOR (tumor protein p53 inducible nuclear protein 2) is located in the nucleolus. It is ubiquitously present in the tissues, with a high metabolism level. TP53INP2 is located on human chromosome 20q11.22.

Immunogeno

The antiserum was produced against synthesized peptide derived from human TP53INP2.

Immunogen Range: 1-50

Azioni biochim/fisiol

TP53INP2/DOR (tumor protein p53 inducible nuclear protein 2) acts as a promoter of autophagy and is involved in cell catabolism. It is essential for rDNA transcription. TP53INP2 is required for protein synthesis and cell proliferation. It also acts as a coactivator of the thyroid hormone receptor and regulates the activities of thyroid hormone.

Caratteristiche e vantaggi

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Stato fisico

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Non trovi il prodotto giusto?  

Prova il nostro Motore di ricerca dei prodotti.

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

nwg

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Scegli una delle versioni più recenti:

Certificati d'analisi (COA)

Lot/Batch Number
3111320

Non trovi la versione di tuo interesse?

Se hai bisogno di una versione specifica, puoi cercare il certificato tramite il numero di lotto.

Cerca un COA

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

TP53INP2/DOR, a mediator of cell autophagy, promotes rDNA transcription via facilitating the assembly of the POLR1/RNA polymerase I preinitiation complex at rDNA promoters.
Xu Y, et al.
Autophagy, 12(7), 1118-1128 (2016)
Takaya Ishihara et al.
Cancer science, 99(10), 1940-1949 (2008-11-20)
Anaplastic thyroid carcinoma (ATC) is one of the most virulent of all human malignancies, with a mean survival time among patients of less than 1 year after diagnosis. To date, however, cytogenetic information on this disease has been very limited.
Hamish Crerar et al.
Neuron, 102(3), 553-563 (2019-03-12)
Neurons are extraordinarily large and highly polarized cells that require rapid and efficient communication between cell bodies and axons over long distances. In peripheral neurons, transcripts are transported along axons to growth cones, where they are rapidly translated in response

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.