SAB4501598

Anti-JAK1 antibody produced in rabbit

affinity isolated antibody

• Sinonimo/i: JAK-1, JAK1, JAK1A, Janus kinase 1, kinase Jak1
• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Coniugato: unconjugated
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Forma fisica: buffered aqueous solution
• PM: antigen 131 kDa
• Reattività contro le specie: rat, mouse, human
• Concentrazione: ~1 mg/mL
• tecniche: ELISA: 1:10000; immunofluorescence: 1:100-1:500; immunohistochemistry: 1:50-1:100
• N° accesso NCBI: P23458
• N° accesso UniProt: P23458
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... JAK1(3716)

Descrizione

Descrizione generale

Anti-JAK1 Antibody detects endogenous levels of total JAK1 protein.

Janus kinase 1 (JAK1) is a non-receptor tyrosine kinase, that belongs to the JAK family. It is located on human chromosome 1p31.3.

Immunogeno

The antiserum was produced against synthesized peptide derived from human JAK1.

Immunogen Range: 91-140

Azioni biochim/fisiol

Mutations in janus kinase 1 (JAK1) results in leukemia, breast cancer, lung cancer and HCC (hepatocellular carcinoma). It participates in signaling with many cytokines. JAK1 is also involved in the immune response and the initiation of allergic airway disease.

Caratteristiche e vantaggi

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Stato fisico

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): nwg
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable