SAB4300263

Anti-phospho-CFL1/CFL2 (pTyr⁸⁸) antibody produced in rabbit

affinity isolated antibody

• Sinonimo/i: Anti-CFL antibody produced in rabbit, Anti-NEM7 antibody produced in rabbit, Anti-cofilin 1 (non-muscle) / cofilin 2 (muscle) antibody produced in rabbit
• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Coniugato: unconjugated
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Forma fisica: buffered aqueous solution
• PM: ~19 kDa
• Reattività contro le specie: human, mouse, rat
• Concentrazione: 1 mg/mL
• tecniche: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
• Isotipo: IgG
• Sequenza immunogenica: (A-T-YP-E-T)
• N° accesso NCBI: NP_005498.1; NP_068733.1
• N° accesso UniProt: P23528
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: phosphorylation (pTyr88)
• Informazioni sul gene: human ... CFL1(1072) , CFL2(1073)

Descrizione

Immunogeno

Peptide sequence around phosphorylation site of tyrosine 88 (A-T-Y(p)-E-T), according to the protein CFL1/CFL2.

Caratteristiche e vantaggi

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Descrizione del bersaglio

Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods.

Stato fisico

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable