SAB2501761

Anti-ZNF703 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

• Sinonimo/i: FLJ14299, ZNF503L, hypothetical protein LOC80139, zinc finger protein 703
• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Origine biologica: goat
• Livello qualitativo: 100
• Coniugato: unconjugated
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Forma fisica: buffered aqueous solution
• Reattività contro le specie: pig, canine, human
• tecniche: indirect ELISA: suitable; western blot: suitable
• N° accesso UniProt: Q9H7S9
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... ZNF703(80139)

Descrizione

Descrizione generale

ZNF703 (zinc finger protein 703) belongs to the NET (Noc/Nlz, Elbow, and Tlp-1) protein family, and the corresponding gene is localized to human chromosome 8p12.

Immunogeno

Peptide with sequence C-ELDKKDQEPKPSPE, from the internal region of the protein sequence according toNP_079345.1

Azioni biochim/fisiol

ZNF703 (zinc finger protein 703) is a frequently modified gene in the pan-cancer group. In zebrafish and Drosophila, it plays an essential role in embryonic development. Amplification of this gene leads to loss of cell-cell adhesion, and thus, an increase in proliferation and migration. In patients with head and neck squamous cell carcinomas (HNSCC), the overexpression of this protein is linked with poor overall survival. It functions as an oncogene in luminal B breast cancer and gastric cancer, and in colorectal cancer (CRC) it facilitates tumor proliferation and invasion. In CRC patients, it is linked with poor prognosis.

Caratteristiche e vantaggi

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Stato fisico

Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable