SAB1300556

Anti-NR6A1 (C-term) antibody produced in rabbit

Ig fraction of antiserum, buffered aqueous solution

• Sinonimo/i: Anti-GCNF, Anti-Germ cell nuclear factor, Anti-HGCNF, Anti-RTR, Retinoid receptor-related testis-specific receptor
• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Coniugato: unconjugated
• Forma dell’anticorpo: Ig fraction of antiserum
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Forma fisica: buffered aqueous solution
• Reattività contro le specie: human
• tecniche: indirect ELISA: 1:1000; western blot: 1:100-1:500
• N° accesso NCBI: NP_201591
• N° accesso UniProt: Q15406
• Condizioni di spedizione: dry ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... NR6A1(2649)

Descrizione

Descrizione generale

NR6A1 has been shown to affect gene expression in embryogenesis and spermatogenesis and is essential for embryonic survival and normal development. Loss of NR6A1 causes embryonic lethality and disrupts normal somitogenesis as well as neural-tube and axis formation. NR6A1 binds as a homodimer to the DR0 DNA response element and has been shown to regulate transcription of genes including protamines 1 and 2 and Oct4. NR6A1 repression function has been shown to be mediated by interaction with the co-repressors N-COR and SMRT in the absence of ligand.

Immunogeno

NR6A1 (NP_201591, 340-375)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human NR6A1.

Stato fisico

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): nwg
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable