RAB1320

Human Cathepsin Z ELISA

for serum, plasma and cell culture supernatants

• Codice UNSPSC: 12352200

Proprietà

• Reattività contro le specie: human
• tecniche: ELISA: suitable
• input: sample type serum; sample type plasma; sample type cell culture supernatant(s)
• assay range: inter-assay cv: <12%; intra-assay cv: <10%
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• Informazioni sul gene: human ... CTSZ(1522)

Descrizione

Descrizione generale

Cathepsins are normally localized in lysosomes of almost all mammalian cells, but under certain conditions they can be secreted from the cells that take part in local proteolysis. Cathepsin Z is a cysteine protease, predominantly expressed in immune cells including monocytes, macrophages or dendritic cells.

This ELISA antibody pair detects Human Cathepsin Z (CTSZ/Cathepsin X/Cathepsin P)

Applicazioni

For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.

Azioni biochim/fisiol

Cathepsins are lysosomal proteases that play an important role in the intracellular degradation of exogenous and endogenous proteins, activation of enzyme precursors, and tumor invasion and metastasis. Cathepsin Z is known to be associated with the pathogenesis of cancer and promotes the development and proliferation of tumor cells. Cathepsin Z mediates the process of proliferation, migration, maturation, adhesion, signal transduction and phagocytosis of immune cells.

Altre note

A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.

Informazioni sulla sicurezza

• Pittogrammi: GHS05
• Avvertenze: Warning
• Indicazioni di pericolo: H290
• Consigli di prudenza: P234 - P390
• Classi di pericolo: Met. Corr. 1
• Codice della classe di stoccaggio: 8A - Combustible corrosive hazardous materials
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable