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RAB0386

Sigma-Aldrich

Brain Natriuretic Peptide EIA Kit

for serum, plasma, culture supernatant and cell lysates

Sinonimo/i:

Gamma-brain natriuretic peptide, Natriuretic peptides B , BNP

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1 KIT
500,00 €

500,00 €


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Cambia visualizzazione
1 KIT
500,00 €

About This Item

Codice UNSPSC:
41123300
NACRES:
NA.32

500,00 €


Per informazioni sulla disponibilità, contatta il Servizio Clienti.

Reattività contro le specie

human, mouse, rat

Confezionamento

kit of 96 wells (12 strips x 8 wells)

tecniche

ELISA: suitable
enzyme immunoassay: suitable

input

sample type serum
sample type culture supernatant(s)
sample type plasma
sample type cell lysate

assay range

inter-assay cv: <15%
intra-assay cv: <10%
sensitivity: 1.66 pg/mL
standard curve range: 0.1–1000 pg/mL

Metodo di rivelazione

colorimetric

Condizioni di spedizione

wet ice

Temperatura di conservazione

−20°C

Informazioni sul gene

human ... NPPB(4879)

Descrizione generale

The BNP Enzyme Immunoassay (EIA) Kit is an in vitro quantitative assay for detecting BNP peptide based on the principle of Competitive Enzyme Immunoassay.

Immunogeno

Brain Natriuretic Peptide, synthetic peptide

Applicazioni

For research use only. Not for use in diagnostic procedures.
Brain natriuretic peptide EIA Kit has been used to measure brain natriuretic peptide (BNP) secreted in human neonatal ventricular cardiomyocyte culture.[1][2]

Azioni biochim/fisiol

Brain natriuretic peptide (BNP) expressed in mammalian brain and atrial natriuretic peptide (ANP) facilitates various physiological functions including regulation of blood pressure and cardiac remodeling.[3] BNP acts as a potential biomarker of high left ventricular end-diastolic pressure in patients with symptomatic left ventricular (LV) dysfunction.[4] Elevated expression of BNP is observed in acute myocardial infarction (AMI) patients. BNP is also implicated in several biological functions such as diuresis, natriureis, hypotensive action and inhibition of aldosterone secretion.[3]

I componenti del kit sono disponibili anche separatamente

N° Catalogo
Descrizione
SDS

  • RABHRP3HRP-StreptavidinSDS

Pittogrammi

Corrosion

Avvertenze

Warning

Indicazioni di pericolo

Consigli di prudenza

Classi di pericolo

Met. Corr. 1

Codice della classe di stoccaggio

8A - Combustible corrosive hazardous materials

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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Certificati d'analisi (COA)

Lot/Batch Number

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A new natriuretic peptide in porcine brain.
Sudoh T
Nature, 332(6159), 78-81 (1988)
Azar Hosseini et al.
Frontiers in pharmacology, 13, 909079-909079 (2022-06-28)
Background: Doxorubicin as an anti-cancer drug causes cardiotoxicity, limiting its tolerability and use. The mechanism of toxicity is due to free radical production and cardiomyocytes injury. This research evaluated Rheum turkestanicum (R.turkestanicum) extract against doxorubicin cardiotoxicity due to its considerable
Plasma brain natriuretic peptide as a biochemical marker of high left ventricular end-diastolic pressure in patients with symptomatic left ventricular dysfunction.
Maeda K
American Heart Journal, 135(5 pt 1), 825-832 (1998)
Héctor Fernández-Susavila et al.
Journal of the American Heart Association, 6(12) (2017-12-06)
Besides the relevant role of brain-type natriuretic peptide (BNP) as biomarker of cardioembolic strokes, new experimental evidences suggest that this peptide may mediate neuroprotective effects. In this study, we have evaluated for the first time the clinical association between BNP
Csaba Matyas et al.
Hepatology (Baltimore, Md.), 71(4), 1391-1407 (2019-08-31)
Hepatic cardiomyopathy, a special type of heart failure, develops in up to 50% of patients with cirrhosis and is a major determinant of survival. However, there is no reliable model of hepatic cardiomyopathy in mice. We aimed to characterize the

Domande

  1. What is the stability of the anti-BNP antibody concentrate (item N reconstituted with 55 ul of 1X Assay Diluent) from RAB0386 when stored at 4C?

    1 risposta
    1. Storing and reusing the reconstituted antibody item N is not recommended as it is not stable when stored. The kit includes 2 vials so that a partial plate may be run.

      Utile?

Recensioni

Nessuna valutazione

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