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RAB0188

Sigma-Aldrich

Human FGF-7 ELISA Kit

for serum, plasma, cell culture supernatant and urine

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1 KIT
608,00 €

608,00 €

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1 KIT
608,00 €

About This Item

Codice UNSPSC:
41116158
NACRES:
NA.32

608,00 €

Per informazioni sulla disponibilità, contatta il Servizio Clienti.

Reattività contro le specie

human

Confezionamento

kit of 96 wells (12 strips x 8 wells)

tecniche

ELISA: suitable
capture ELISA: suitable

input

sample type cell culture supernatant(s)
sample type plasma
sample type urine
sample type serum

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.5 pg/mL
standard curve range: 0.55-400 pg/mL

Metodo di rivelazione

colorimetric

Condizioni di spedizione

wet ice

Temperatura di conservazione

−20°C

Informazioni sul gene

human ... FGF7(2252)

Categorie correlate

Descrizione generale

The Human FGF-7 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human FGF-7 in serum, plasma, cell culture supernatants and urine.
The gene FGF7 (fibroblast growth factor 7) is mapped to human chromosome 15q21.1.[1] The encoded protein belongs to the fibroblast growth factor family and is secreted by mesenchymal cells.[2][3]

Immunogeno

Recombinant Human FGF7

Applicazioni

Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Azioni biochim/fisiol

FGF7 (fibroblast growth factor 7) is involved in the development of skin and sweat glands, wound healing and cutaneous homeostasis.[4] It controls keratinocyte differentiation and viability by modulating autophagy.[2] FGF7 also participates in embryonic development, tumorigenesis, cell proliferation, migration and differentiation.[3] It is linked with several disorders like nonsyndromic cleft lip and palate, thyroid volume, goiter risk and chronic obstructive pulmonary disease. FGF7 plays an important role in the morphology of developing lungs. Absence of the FGF7 activity decreases airway branching during development. During injury, it is involved in airway repair.[5]

Altre note

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

I componenti del kit sono disponibili anche separatamente

N° Catalogo
Descrizione
SDS
  • RABELADEELISA 5X Assay/Sample Diluent Buffer E (Item E2)SDS
  • RABSTOP3ELISA Stop Solution (Item I)SDS
  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS
  • RABWASH420X Wash Buffer (Item B)SDS

Pittogrammi

Corrosion
GHS05

Avvertenze

Warning

Indicazioni di pericolo

H290

Consigli di prudenza

P234 - P390

Classi di pericolo

Met. Corr. 1

Codice della classe di stoccaggio

8A - Combustible corrosive hazardous materials

Scegli una delle versioni più recenti:

Certificati d'analisi (COA)

Lot/Batch Number
1005J0245
0922J0245
0324J0245
0803I0245
0706I0245

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Se hai bisogno di una versione specifica, puoi cercare il certificato tramite il numero di lotto.

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Association between fibroblast growth factor 7 and the risk of chronic obstructive pulmonary disease
Xu SC, et al.
Acta Pharmacologica Sinica, 33(8), 998-1003 (2012)
Recombinant keratinocyte growth factor 1 in tobacco potentially promotes wound healing in diabetic rats
Feng ZG, et al.
BioMed Research International (2014)
FGF7 Over Expression is an Independent Prognosticator in Patients with Urothelial Carcinoma of the Upper Urinary Tract and Bladder
Fan EW, et al.
The Journal of Urology, 194(1), 223-229 (2015)
Oncogenic mutations of ALK kinase in neuroblastoma
Chen Y, et al.
Nature, 455(7215), 971-974 (2008)
Role of Keratinocyte Growth Factor in the Differentiation of Sweat Gland-Like Cells From Human Umbilical Cord-Derived Mesenchymal Stem Cells.
Xu Y
Stem Cells Translational Medicine, 5(1), 106-116 (2016)

Domande

1–3 di 3 domande  

  1. What is the specificity of the Human FGF7 ELISA antibodies (RAB0188)?

    1 risposta

    1. The capture antibody utilized in this kit is a mouse monoclonal antibody with an immunogen of aa32-194 of human FGF-7 (accession # P21781). Meanwhile, the detection antibody is a goat polyclonal antibody with the immunogen of aa32-194 of human FGF-7 (accession # Q6FGV5).

      Utile?

  2. Will the Human FGF-7 ELISA kit (BAB0188) detect mouse FGF7?

    1 risposta

    1. The Human FGF-7 ELISA kit has not been tested for cross-reactivity to mouse, so we cannot confirm if it can detect mouse FGF-7. However, we do offer a Mouse FGF-7 ELISA with the catalog number RAB1123.

      Utile?

  3. Is there a detailed protocol for this (the general sandwich protocol is not specific enough)? E.g. the kit FGF-7 concentrate for the standard curve - no concentration is written on the vial. And there is no information on how to make serial dilutions.

    1 risposta

    1. Using the lot number on the product you purchased, you can access the lot-specific CofA to view the procedure and concentration. Example CofA using lot number 0922J0245: https://www.sigmaaldrich.com/certificates/Graphics/COfAInfo/SigmaABNO/RAB0188_0922J0245.pdf

      Utile?

Recensioni

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