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RAB0028

Sigma-Aldrich

Human BMP2 ELISA Kit

for serum, plasma, cell culture supernatant and urine

Sinonimo/i:

BMP-2, Bone morphogenetic protein 2

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali


About This Item

Codice UNSPSC:
41116158
NACRES:
NA.32

Reattività contro le specie

human

Confezionamento

kit of 96 wells (12 strips x 8 wells)

tecniche

ELISA: suitable
capture ELISA: suitable

input

sample type serum
sample type cell culture supernatant(s)
sample type urine
sample type plasma

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 45 pg/mL
standard curve range: 46.88-3000 pg/mL

Metodo di rivelazione

colorimetric

Condizioni di spedizione

wet ice

Temperatura di conservazione

−20°C

Informazioni sul gene

human ... BMP2(650)

Descrizione generale

BMP2 (bone morphogenetic protein 2) is encoded by the gene mapped to human chromosome 20p12.3. The encoded protein belongs to transforming growth factor-β (TGFβ) superfamily. BMP-2 is expressed in heart, lung, and dorsal aorta.
The Human BMP-2 ( Bone morphogenetic proteins-2) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme- linked immunosorbent assay for the quantitative measurement of human BMP-2 in serum, plasma, cell culture supernatants and urine.

Immunogeno

Recombinant Human BMP2

Applicazioni

For research use only. Not for use in diagnostic procedures.
Human BMP2 (bone morphogenetic protein 2) ELISA kit has been used for measuring concentrations of BMP in conditioned mouse organoid media.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Azioni biochim/fisiol

BMP2 (bone morphogenetic protein 2) plays a vital role in the activation of the autonomic lineage-specific basic–helix-loop-helix protein MASH1 (mammalian achaete scute homolog-1) and in the autonomic neurogenesis in neural crest stem cells in vitro. During bone repair, BMP-2 controls the expression of Runt-related transcription factor 2 (Runx2) and Osterix (Osx), thereby enhancing migration, proliferation and osteogenic differentiation of mesenchymal stem cells. In addition to its osteogenic activity, BMP-2 also plays an important role in cardiac morphogenesis. Recombinant human bone morphogenetic protein-2 (rhBMP-2) plays an essential role in pathogenesis of oral squamous cell carcinomas. Mutation in BMP-2 gene is associated with osteoporosis.

Altre note

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

I componenti del kit sono disponibili anche separatamente

N° Catalogo
Descrizione
SDS

  • RABELADAELISA 1X Assay/Sample Diluent Buffer A (Item D1)SDS

  • RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)SDS

  • RABSTOP3ELISA Stop Solution (Item I)SDS

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS

  • RABWASH420X Wash Buffer (Item B)SDS

Pittogrammi

Corrosion

Avvertenze

Warning

Indicazioni di pericolo

Consigli di prudenza

Classi di pericolo

Met. Corr. 1

Codice della classe di stoccaggio

8A - Combustible corrosive hazardous materials


Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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