PHG0004

BIS-TRIS

• Sinonimo/i: 2,2-bis(idrossimetil)-2,2′,2″-nitrilotrietanolo, 2-bis(2-idrossietil)ammino-2-(idrossimetil)-1,3-propandiolo, Bis(2-idrossietil)ammino-tris(idrossimetil)metano
• Formula empirica (notazione di Hill): C₈H₁₉NO₅
• Numero CAS: 6976-37-0
• Peso molecolare: 209.24
• Beilstein: 2205275
• Numero CE: 230-237-7
• Numero MDL: MFCD00002853
• Codice UNSPSC: 12161705
• NACRES: NA.21

Proprietà

• Origine biologica: synthetic
• Livello qualitativo: 400
• Stato: powder
• tecniche: cell culture | mammalian: suitable
• Impurezze: Endotoxin, microbial, and trace metals; tested
• Intervallo di pH utile: 5.8-7.2
• pKa (25 °C): 6.5
• Solubilità: H₂O: 0.1 M, clear, colorless
• Compatibilità: suitable for manufacturing use
• Attività estranea: Cytotoxicity, DNase, NICKase, RNase, and Protease; tested
• Stringa SMILE: OCCN(CCO)C(CO)(CO)CO
• InChI: 1S/C8H19NO5/c10-3-1-9(2-4-11)8(5-12,6-13)7-14/h10-14H,1-7H2; OWMVSZAMULFTJU-UHFFFAOYSA-N

Descrizione

Descrizione generale

Our SAFC^® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Buffer quality is vital for the success of biopharmaceutical processes, because buffers are indispensable in nearly every production step.

Our broad portfolio of buffer materials manufactured under appropriate controls is tailored to your needs. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.

Applicazioni

Bis Tris is a commonly used biological buffer for very broad usage in biological systems such as diagnostics, electrophoresis and protein based bioprocessing. The pKa of Bis Tris is 6.36 which makes it a good candidate for biological-based formulations.

Bis Tris is used in a wide variety of biological applications including protein separation buffers, cell culture media, electrophoresis separations and diagnostic reagent formulations.

Note legali

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Pittogrammi: GHS07
• Avvertenze: Warning
• Indicazioni di pericolo: H319
• Consigli di prudenza: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Classi di pericolo: Eye Irrit. 2
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable