P6744

Picric acid solution

1.3% in H₂O (saturated)

• Sinonimo/i: 2,4,6-Trinitrophenol
• Formula condensata: (O₂N)₃C₆H₂OH
• Numero CAS: 88-89-1
• Peso molecolare: 229.10
• Beilstein: 423400
• Numero MDL: MFCD00007102
• Codice UNSPSC: 12171500
• ID PubChem: 24898790
• NACRES: NA.47

Proprietà

• Forma fisica: liquid
• Concentrazione: 1.3% in H₂O (saturated)
• Colore: yellow to very dark yellow
• Densità: 1.080 g/cm³
• applicazioni: hematology; histology
• Temperatura di conservazione: room temp
• Stringa SMILE: Oc1c(cc(cc1[N+]([O-])=O)[N+]([O-])=O)[N+]([O-])=O
• InChI: 1S/C6H3N3O7/c10-6-4(8(13)14)1-3(7(11)12)2-5(6)9(15)16/h1-2,10H; OXNIZHLAWKMVMX-UHFFFAOYSA-N

Descrizione

Descrizione generale

Picric acid is a polynitrated aromatic acid. It dissolves in water to form a solution with low pH (pH 2.0). It interacts with basic groups of proteins, forms salts and coagulates them. Fixation with picric acid gives a bright stain, but there might be a loss of nucleic acids due to the low pH of the solution.
Picric acid is anionic and has a low molecular weight.

Applicazioni

Picric acid is commonly used as a fixative and staining reagent in forensic and histological applications. It is a general cytoplasmic stain, connective tissue fiber stain, and a fixative for tissues.

• It is a component of picrosirius red which is used to stain collagen.
• Bouin’s fluid which also comprises picric acid is a fixative for nuclei and connective tissue.
• It can be used as a colorimetric reagent in creatinine determination assay.

Informazioni sulla sicurezza

• Rischi supp: EUH001
• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Faceshields, Gloves