P3493

Monoclonal Anti-Placenta Growth Factor-2 antibody produced in rat

clone 62526, purified immunoglobulin, lyophilized powder

• Sinonimo/i: Anti-PlGF-2
• Numero MDL: MFCD02097209
• Codice UNSPSC: 51111800
• NACRES: NA.41

Proprietà

• Origine biologica: rat
• Livello qualitativo: 100
• Coniugato: unconjugated
• Forma dell’anticorpo: purified immunoglobulin
• Tipo di anticorpo: primary antibodies
• Clone: 62526, monoclonal
• Forma fisica: lyophilized powder
• Reattività contro le specie: mouse
• tecniche: indirect ELISA: 0.5-1.0 μg/mL; neutralization: suitable; western blot: 1-2 μg/mL
• Isotipo: IgG2a
• N° accesso UniProt: P49764
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: mouse ... Pgf(18654)

Descrizione

Descrizione generale

The antibody neutralizes receptor-ligand interaction. The antibody shows no cross-reactivity with recombinant human PlGF and recombinant human VEGF.

Immunogeno

purified recombinant mouse placenta growth factor 2 expressed in insect Sf 21 cells.

Azioni biochim/fisiol

Placental growth factors (PlGF) are involved in the growth, migration and survival of endothelial cells. All the four isoforms identified are expressed in placenta and umbilical vein endothelial cells. PlGF bind to specific Flt-1 receptors that result in activation and recruitment of dendritic cells, smooth muscle cells and inflammatory cells. PlGF2 has the ability to bind heparin while PlGF1 is a soluble isoform.

Stato fisico

Lyophilized from a 0.2 μm filtered solution of phosphate buffered saline with 5% trehalose.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)