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P2363

Protein Kinase G II from rat

>90% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf9 cells, solution

Sinonimo/i:

Protein Kinase, 3′,5′-Cyclic GMP Dependent from rat

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Informazioni su questo articolo

UNSPSC Code:
41106305
NACRES:
NA.32
MDL number:
MFCD03444648
Specific activity:
~0.7 U/mg
Assay:
>90% (SDS-PAGE)
Recombinant:
expressed in baculovirus infected Sf9 cells

recombinant

expressed in baculovirus infected Sf9 cells

Quality Segment

200

assay

>90% (SDS-PAGE)

form

solution

specific activity

~0.7 U/mg

UniProt accession no.

Q64595

shipped in

dry ice

storage temp.

−20°C

Gene Information

rat ... Prkg2(25523)

General description

Protein kinase, cGMP-dependent, type II (PRKG2), also known as type II cGMP-dependent protein kinase (cGK), is encoded by the gene mapped to human chromosome 4q13.1–q21.1.

Biochem/physiol Actions

Protein kinase, cGMP-dependent, type II (PRKG2) is implicated in the regulation of intestinal fluid balance in man. The encoded protein plays an essential role in proliferative to hypertrophic transition of growth plate chondrocytes during endochondral ossification. Loss of PRKG2 function is associated with the development of renal cysts, intellectual disability and speech defect. In rodent and bovine models, deletion of the gene leads to dwarfism.

Other Notes

One unit will phosphorylate one μmole of VASPtide (RRKVSKQE) per minute at pH 7.4

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Questo articolo
P6998P3738C8482
Protein Kinase G II from rat >90% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf9 cells, solution

Sigma-Aldrich

P2363

Protein Kinase G II from rat

Protein Kinase A Catalytic Subunit β, Active human recombinant, expressed in baculovirus infected Sf9 cells, ≥80% (SDS-PAGE), buffered aqueous glycerol solution

Sigma-Aldrich

P6998

Protein Kinase A Catalytic Subunit β, Active human

Protein Kinase G Iβ human ≥95% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf9 cells, buffered aqueous glycerol solution

Sigma-Aldrich

P3738

Protein Kinase G Iβ human

Protein Kinase A catalytic subunit human >90% (SDS-PAGE), recombinant, expressed in E. coli, buffered aqueous glycerol solution

Sigma-Aldrich

C8482

Protein Kinase A catalytic subunit human

assay

>90% (SDS-PAGE)

assay

≥80% (SDS-PAGE)

assay

≥95% (SDS-PAGE)

assay

>90% (SDS-PAGE)

specific activity

~0.7 U/mg

specific activity

≥10 nmol/min·mg

specific activity

≥1.5 units/mg protein (20-fold stimulation by cGMP (5 μM))

specific activity

>1000 units/mg protein

Gene Information

rat ... Prkg2(25523)

Gene Information

human ... PRKACB(5567)

Gene Information

human ... PRKG1(5592)

Gene Information

human ... PRKACA(5566)

recombinant

expressed in baculovirus infected Sf9 cells

recombinant

expressed in baculovirus infected Sf9 cells

recombinant

expressed in baculovirus infected Sf9 cells

recombinant

expressed in E. coli

form

solution

form

buffered aqueous glycerol solution

form

buffered aqueous glycerol solution

form

buffered aqueous glycerol solution

storage temp.

−20°C

storage temp.

−70°C

storage temp.

−20°C

storage temp.

−70°C

Classe di stoccaggio

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Elenchi normativi

Forniamo informazioni su eventuali restrizioni prevalentemente per i prodotti chimici. Per altre tipologie di prodotto siamo in grado di fornire soltanto informazioni limitate. Nessuna segnalazione significa che nessuno dei componenti è citato in un elenco. È dovere dell’utilizzatore assicurarsi che il prodotto venga impiegato in maniera sicura e a norme di legge.

127087-87-0

CAS No.

127087-87-0

CAS No.

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