N214

Neutrophil Activating Peptide-2 human

>97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

• Sinonimo/i: NAP-2
• Numero MDL: MFCD00241917
• Codice UNSPSC: 51111800

Proprietà

• Origine biologica: human
• Ricombinante: expressed in E. coli
• Saggio: >97% (SDS-PAGE)
• Forma fisica: lyophilized powder
• Potenza: 0.1-0.3 μg/mL ED₅₀ (cytochalasin B treated human neutrophils); 0.1-0.5 ng/mL ED₅₀ (BaF/3 hCXCR-2 transfected cells)
• PM: ~7.6 kDa
• Condizioni di stoccaggio: avoid repeated freeze/thaw cycles (Storage in "frost-free" freezers is not recommended)
• tecniche: cell culture | mammalian: suitable
• Impurezze: endotoxin, tested
• N° accesso UniProt: P02775
• Temperatura di conservazione: −20°C
• Informazioni sul gene: human ... PPBP(5473)

Descrizione

Azioni biochim/fisiol

Neutrophil Activating Peptide-2, a member of the CXC chemokine family, chemoattracts and activates neutrophils and also binds CXCR-2. NAP-2 is proteolytically processed C-terminal fragments of platelet basic protein (PBP), which is found in the α-granules of human platelets.

Stato fisico

Lyophilized from a 0.2 μm filtered solution in 30% acetonitrile and 0.1% trifluoroacetic acid containing 0.5 mg bovine serum albumin.

Risultati analitici

The biological activity is measured by the induction of myeloperoxidase release from cytochalasin B treated human neutrophils.