M6309

Anti-Matrix Metalloproteinase-23, Hinge Region antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution

• Sinonimo/i: Anti-MMP-23
• Numero MDL: MFCD03097011
• Codice UNSPSC: 12352203

Proprietà

• Origine biologica: rabbit
• Coniugato: unconjugated
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Stato: buffered aqueous glycerol solution
• PM: antigen (active form) 45 kDa; antigen (pro-form) 58 kDa
• Reattività contro le specie: human
• Concentrazione: ~1 mg/mL
• tecniche: immunohistochemistry (frozen sections): suitable; immunoprecipitation (IP): suitable; indirect ELISA: suitable; western blot: 1:1,000
• N° accesso UniProt: P50281
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... MMP14(4323)

Descrizione

Descrizione generale

Matrix metalloproteinase-23B (MMP-23B) possesses regions which are rich in amino acids like proline and cysteine. The MMP-23B gene is localized on human chromosome 1p36.

Specificità

Reacts with reduced and non-reduced MMP-23. Recognizes the pro-form and active forms of MMP-23 as well as a series of further cleaved active forms.

Immunogeno

synthetic peptide corresponding to the hinge region of human matrix metalloproteinase-23 (MIFR-2, CA-MMP).

Azioni biochim/fisiol

Matrix metalloproteinase-23B (MMP-23B) is part of the matrix metalloproteinase family of proteins, which take part in the remodeling of the extracellular matrix.

Stato fisico

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 50% glycerol and 15 mM sodium azide.