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K2126

Sigma-Aldrich

β-Estradiol-6-one 6-(O-carboxymethyloxime)

≥98.00% (TLC), powder

Sinonimo/i:

β-Estradiol-6-(O-carboxymethyl)oxime, 1,3,5(10)-Estratriene-3,17β-diol-6-one6-(O-carboxymethyloxime), 3,17β-Dihydroxy-1,3,5(10)-estratriene 6-(O-carboxymethyl)oxime, 6-Ketoestradiol 6-(O-carboxymethyloxime)

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About This Item

Formula empirica (notazione di Hill):
C20H25NO5
Numero CAS:
35048-47-6
Peso molecolare:
359.42
Beilstein:
2484202
Numero MDL:
MFCD00056459
Codice UNSPSC:
51111800
ID PubChem:
329817132
NACRES:
NA.77

product name

β-Estradiol-6-one 6-(O-carboxymethyloxime),

Origine biologica

synthetic (organic)

Livello qualitativo

200

Saggio

≥98.00% (TLC)

Forma fisica

powder

Solubilità

ethanol: 19.60-20.40 mg/mL, clear, colorless to faintly yellow

Condizioni di spedizione

ambient

Temperatura di conservazione

2-8°C

Stringa SMILE

C[C@]12CC[C@H]3[C@@H](C\C(=N\OCC(O)=O)c4cc(O)ccc34)[C@@H]1CC[C@@H]2O

InChI

1S/C20H25NO5/c1-20-7-6-13-12-3-2-11(22)8-15(12)17(21-26-10-19(24)25)9-14(13)16(20)4-5-18(20)23/h2-3,8,13-14,16,18,22-23H,4-7,9-10H2,1H3,(H,24,25)/b21-17-/t13-,14-,16+,18+,20+/m1/s1
AWARIMYXKAIIGO-UYGYUSPXSA-N

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Descrizione generale

β-Estradiol-6-one 6-(O-carboxymethyloxime) is a derivative of 17β-estradiol.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

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May L Chiu et al.
Biotechnology and applied biochemistry, 58(1), 75-82 (2011-03-31)
A convenient homogeneous enzyme immunoassay for estradiol is described. Unlike heterogeneous immunoassays, which require time-consuming separation steps or expensive automated systems, homogeneous immunoassays, wherein all reagents are freely suspended in bulk solution, can be simple and fast without costly instrumentation.
Mingzhe Liu et al.
Journal of bioscience and bioengineering, 111(5), 564-568 (2011-02-01)
Antibodies were covalently conjugated with poly(ethylene glycol) (PEG) and the properties of the PEGylated antibodies in organic media were investigated. Two types of monoclonal antibody were used in this study. One was a monoclonal antibody (abzyme) that was prepared against
M Bourtourault et al.
Research communications in chemical pathology and pharmacology, 72(3), 273-284 (1991-06-01)
Female rats were immunized with mixed 17 beta-estradiol-6-carboxymethyloxime-bovine serum albumin and testosterone-3-carboxymethyloxime-bovine serum albumin. All the animals produced antibodies against the 2 haptens and were better immunized against 17 beta-estradiol than against testosterone. Nevertheless the disappearance of cyclic ovarian function
F Mao et al.
Yao xue xue bao = Acta pharmaceutica Sinica, 26(8), 611-614 (1991-01-01)
According to the character of structure and activity of the test reagents I-IV, two new reagents V and VI for detecting estrogen receptor of human mammary cancer cells were synthesized. This simplifies the route of synthesis and increases activity. Key
C M Furnival et al.
The British journal of surgery, 70(8), 457-459 (1983-08-01)
The performance of a fluorescent cytochemical oestrogen receptor (ER) assay has been compared with an established dextran-coated charcoal ER assay in 85 cases of primary breast cancer. Both assays were performed on tissue samples from the same tumour, by independent
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