I2250

Indole-5-carboxylic acid

~95% (TLC)

• Sinonimo/i: 5-Carboxyindole
• Formula empirica (notazione di Hill): C₉H₇NO₂
• Numero CAS: 1670-81-1
• Peso molecolare: 161.16
• Beilstein: 124391
• Numero CE: 216-799-6
• Numero MDL: MFCD00005678
• Codice UNSPSC: 12352100
• ID PubChem: 24895968

Proprietà

• Saggio: ~95% (TLC)
• Punto di fusione: 211-213 °C (lit.)
• Temperatura di conservazione: −20°C
• Stringa SMILE: OC(=O)c1ccc2[nH]ccc2c1
• InChI: 1S/C9H7NO2/c11-9(12)7-1-2-8-6(5-7)3-4-10-8/h1-5,10H,(H,11,12); IENZCGNHSIMFJE-UHFFFAOYSA-N

Descrizione

Applicazioni

• Reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles, as potential anticancer immunomodulators
• Reactant for preparation of indolyl-quinolines via metal- and solvent-free autoxidative coupling reaction
• Reactant for preparation of anthranilic acids using bromamine-B oxidant and palladium chloride catalyst
• Reactant for synthesis of indirubin derivatives
• Reactant for preparation of amide conjugates with ketoprofen, as inhibitors of Gli1-mediated transcription in Hedgehog pathway
• Reactant for preparation of piperazine-bisamide analogs as human growth hormone secretagogue receptor antagonists for treatment of obesity

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 13 - Non Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)