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H5520

Sigma-Aldrich

17α-Hydroxyprogesterone hexanoate

≥98%

Sinonimo/i:

17α-Hydroxyprogesterone caproate

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About This Item

Formula empirica (notazione di Hill):
C27H40O4
Numero CAS:
630-56-8
Peso molecolare:
428.60
Numero CE:
211-138-8
Numero MDL:
MFCD00072134
Codice UNSPSC:
12352200
ID PubChem:
24895697

Saggio

≥98%

Stringa SMILE

[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@@]4(C)[C@@]2([H])CC[C@]4(OC(=O)CCCCC)C(C)=O

InChI

1S/C27H40O4/c1-5-6-7-8-24(30)31-27(18(2)28)16-13-23-21-10-9-19-17-20(29)11-14-25(19,3)22(21)12-15-26(23,27)4/h17,21-23H,5-16H2,1-4H3/t21-,22+,23+,25+,26+,27+/m1/s1
DOMWKUIIPQCAJU-LJHIYBGHSA-N

Informazioni sul gene

human ... PGR(5241)

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Azioni biochim/fisiol

Shows significant reduction of pre-term delivery by mothers with a history of premature delivery, with no detectable harm to the infant.

Pittogrammi

Health hazard
GHS08

Avvertenze

Danger

Indicazioni di pericolo

H360

Consigli di prudenza

P201 - P308 + P313

Classi di pericolo

Repr. 1B

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificati d'analisi (COA)

Lot/Batch Number
073H1027

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Courtney D Cuppett et al.
American journal of obstetrics and gynecology, 208(1), 86-86 (2012-10-16)
Plasma concentrations of 17-alpha-hydroxyprogesterone caproate (17-OHPC) vary substantially in pregnant patients who receive an identical dose. Endogenous steroid hormones may alter 17-OHPC metabolism, which contributes to this large variability. Pooled human liver microsomes were incubated with 17-OHPC alone or in
William A Grobman et al.
American journal of obstetrics and gynecology, 207(5), 390-390 (2012-09-27)
We sought to evaluate whether 17 alpha-hydroxyprogesterone caproate (17-OHP) reduces preterm birth (PTB) in nulliparous women with a midtrimester cervical length (CL) <30 mm. In this multicenter randomized controlled trial, nulliparous women with a singleton gestation between 16 and 22
Baha M Sibai et al.
American journal of perinatology, 29(8), 635-642 (2012-05-12)
To examine pregnancy outcomes of women receiving weekly compounded 17 α-hydroxyprogesterone caproate (17P) injections through a home nursing program compared with those reported in a multicenter trial by the Eunice Kennedy Shriver National Institute of Child Health and Human Development
A C Lim et al.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology, 40(4), 426-430 (2012-09-26)
Previous studies on singleton pregnancies have indicated that progestogens may reduce the rate of cervical shortening during pregnancy. The aim of this study was to investigate whether treatment with 17-alpha hydroxyprogesterone caproate (17-OHPC) has an effect on cervical shortening in
Marie-Victoire Senat et al.
American journal of obstetrics and gynecology, 208(3), 194-194 (2013-02-26)
The objective of the study was to evaluate the use of 17 alpha-hydroxyprogesterone caproate (17P) to reduce preterm delivery in women with a twin pregnancy and short cervix. This open-label, multicenter, randomized controlled trial included women with a twin pregnancy
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