G5146

D-(+)-Glucosio

Hybri-Max^™, powder, BioReagent, suitable for hybridoma

• Sinonimo/i: Destrosio
• Formula empirica (notazione di Hill): C₆H₁₂O₆
• Numero CAS: 50-99-7
• Peso molecolare: 180.16
• Beilstein: 1724615
• Numero CE: 200-075-1
• Numero MDL: MFCD00063774
• Codice UNSPSC: 12352201
• ID PubChem: 24895199
• NACRES: NA.75

Proprietà

• Origine biologica: maize
• Livello qualitativo: 200
• Grado: Hybri-Max^™
• Nome Commerciale: BioReagent
• Saggio: ≥99.5%
• Stato: powder
• tecniche: cell culture | hybridoma: suitable
• Impurezze: endotoxin, tested
• Punto di fusione: 150-152 °C (lit.)
• Solubilità: H₂O: 2g + 15 mL (Tested)
• Stringa SMILE: OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O
• InChI: 1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1; WQZGKKKJIJFFOK-DVKNGEFBSA-N
• Informazioni sul gene: human ... PYGM(5837)

Descrizione

Descrizione generale

Glycogen phosphorylase (PYG) exists as brain and muscle isoform. It is expressed in astrocytes and neurons respectively.[1] The PYGM gene is mapped to human chromosome 11q13.1.[2]

Applicazioni

D-(+)-Glucose has been used in cell engineering.[3] It has also been used to perform oral glucose tolerance test.[4]

Azioni biochim/fisiol

Glycogen phosphorylase, muscle associated (PYGM), is an important contributor to glycogenolysis. Down regulation of PYGM gene is observed in schizophrenia.[1] Mutation in PYGM leads to McArdle disease, a glycogen storage disorder.[5] The PYGM gene is significantly associated with energy production.[6]

Nota sulla preparazione

The material may produce a yellowish solution if prepared at a higher concentration than 2g + 15ml.

Note legali

Hybri-Max is a trademark of Sigma-Aldrich Co. LLC

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)