F1305

Anti-FEN-1 (C-terminal) antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous solution

• Sinonimo/i: Anti-Flap endonuclease, Anti-Flap structure-specific endonuclease 1
• Numero MDL: MFCD09039190
• Codice UNSPSC: 12352203

Proprietà

• Origine biologica: rabbit
• Coniugato: unconjugated
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Stato: buffered aqueous solution
• PM: antigen 45 kDa
• Reattività contro le specie: human
• Concentrazione: ~1 mg/mL
• tecniche: immunoprecipitation (IP): 2-4 μg using HEK 293T cell lysates; indirect immunofluorescence: 5-10 μg/mL using paraformaldehyde-fixed HEK 293T cells; western blot: 0.5-1 μg/mL using K562 cell lysates
• N° accesso UniProt: P39748
• Condizioni di spedizione: dry ice
• Temperatura di conservazione: −20°C
• Informazioni sul gene: human ... FEN1(2237) ; mouse ... Fen1(14156) ; rat ... Fen1(84490)

Descrizione

Immunogeno

synthetic peptide corresponding to amino acids 367-380 of human FEN-1, conjugated to KLH via an N-terminal added cysteine residue. The corresponding sequence in rat and mouse differs by one and two amino acids, respectively.

Descrizione del bersaglio

FEN-1 (C-terminal) encodes a protein that removes 5′ overhanging flaps in DNA repair and processes the 5′ ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long-patch b

Stato fisico

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)