C1671

Chlorprothixene hydrochloride

• Sinonimo/i: 2-Chloro-9-(3-dimethylaminopropylidene)thioxanthene hydrochloride
• Formula empirica (notazione di Hill): C₁₈H₁₈ClNS · HCl
• Numero CAS: 6469-93-8
• Peso molecolare: 352.32
• NACRES: NA.77
• PubChem Substance ID: 24278300
• UNSPSC Code: 12352200
• EC Number: 229-289-3
• MDL number: MFCD01941605
• Form: powder

Proprietà

• form: powder
• storage temp.: 2-8°C
• SMILES string: Cl.CN(C)CC\C=C1\c2ccccc2Sc3ccc(Cl)cc13
• InChI: 1S/C18H18ClNS.ClH/c1-20(2)11-5-7-14-15-6-3-4-8-17(15)21-18-10-9-13(19)12-16(14)18;/h3-4,6-10,12H,5,11H2,1-2H3;1H/b14-7-;
• InChI key: YWKRLOSRDGPEJR-KIUKIJHYSA-N
• Gene Information: human ... DRD2(1813), DRD3(1814), HTR2A(3356), HTR2C(3358)

Descrizione

General description

Chlorprothixene is a neuroleptic drug, which belongs to thioxanthene group. It has anticholinergic effects. Chlorprothixene might be associated with obstructive jaundice and parkinsonism. It is used to treat psychosis.

Application

Chlorprothixene hydrochloride has been used to study its exposure effects on learning and memory of rats.

Biochem/physiol Actions

D₂ dopamine receptor antagonist; blocks a subset of GABA_A receptors in rat cortex that is also blocked by clozapine; thioxanthine antipsychotic.

Informazioni sulla sicurezza

• pictograms: GHS06
• signalword: Danger
• hcodes: H301
• pcodes: P301 + P310
• Hazard Classifications: Acute Tox. 3 Oral
• Classe di stoccaggio: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable