C0984
Creatine Kinase MB Fraction from human heart
≥70% (SDS-PAGE), liquid
Sinonimo/i:
CK MB Fraction
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About This Item
Prodotti consigliati
Origine biologica
human heart
Livello qualitativo
Saggio
≥70% (SDS-PAGE)
Forma fisica
liquid
Concentrazione
≥0.5 mg/mL
tecniche
IR spectroscopy: suitable
Compatibilità
suitable for tissue
applicazioni
pharmaceutical
Temperatura di conservazione
−20°C
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Descrizione generale
Research area: Cell Signaling
Creatine Kinase (CK) comprises M and B subunit and is a dimeric molecule. It is one among the isoenzymes of CK. The enzyme is majorly present in the myocardium.
Creatine Kinase (CK) comprises M and B subunit and is a dimeric molecule. It is one among the isoenzymes of CK. The enzyme is majorly present in the myocardium.
Applicazioni
Creatine Kinase MB Fraction from human heart has been used:
- as a diagnostic marker for acute myocardial infarction.
- to identify overlapping absorbance peaks between blood and the cardiac biomarkers.
- to study the phosphorylation pathway of dioxolane guanosine (DXG) in vivo, a potential treatment of HIV-1 infection.
Azioni biochim/fisiol
Creatine Kinase (CK) catalyzes the formation of creatinine from creatine phosphate. The enzyme is associated with coronary performance. Elevated serum levels of CK-MB are prime indicators of myocardial cellular injury. It is regarded as a “gold standard” for myocardial infarction diagnosis. The levels of cardiac troponin I (cTnI) or cardiac troponin T also correlate to higher CK-MB) levels. CK-MB levels may also be elevated in chronic renal failure.
Componenti
Solution in 5 mM sodium succinate, 10 mM sodium chloride, 1 mM EDTA, 5 mM β-mercaptoethanol, 50% glycerol, pH 7.0.
Applicazioni
N° Catalogo
Descrizione
Determinazione del prezzo
Codice della classe di stoccaggio
10 - Combustible liquids
Classe di pericolosità dell'acqua (WGK)
WGK 1
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Certificati d'analisi (COA)
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I clienti hanno visto anche
Terry M Welsh et al.
Annals of clinical and laboratory science, 32(1), 44-49 (2002-02-19)
The diagnosis of myocardial infarction (MI) is established in patients with chest pain and equivocal electrocardiogram changes by demonstrating a rise in blood levels of creatine kinase MB (CK-MB) and/or an increase in cardiac troponin I (cTnI) or cardiac troponin
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J E Adams et al.
Clinical chemistry, 40(7 Pt 1), 1291-1295 (1994-07-01)
Although measurement of cardiac troponin I (cTnI) is, in some situations, more specific for detection of cardiac injury than is measurement of the MB isoenzyme of creatine kinase (MBCK), its sensitivity and specificity relative to MBCK for detection of myocardial
Anabolism of amdoxovir: phosphorylation of dioxolane guanosine and its 5?-phosphates by mammalian phosphotransferases
Feng JY, et al.
Biochemical Pharmacology, 68(9), 1879-1888 (2004)
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