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Documenti

A0835

Sigma-Aldrich

N-Acetyl-Asp-Glu-Val-Asp-al

≥95%, powder

Sinonimo/i:

Ac-DEVD-CHO

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About This Item

Formula empirica (notazione di Hill):
C20H30N4O11
Numero CAS:
169332-60-9
Peso molecolare:
502.47
Numero MDL:
MFCD00671412
Codice UNSPSC:
12352209
ID PubChem:
24890193
NACRES:
NA.32

Origine biologica

synthetic

Livello qualitativo

100

Saggio

≥95%

Forma fisica

powder

Colore

white

Solubilità

H2O: 1 mg/mL

Temperatura di conservazione

−20°C

Stringa SMILE

[H]C(=O)C(CC(O)=O)NC(=O)C(NC(=O)C(CCC(O)=O)NC(=O)C(CC(O)=O)NC(C)=O)C(C)C

InChI

1S/C20H30N4O11/c1-9(2)17(20(35)22-11(8-25)6-15(29)30)24-18(33)12(4-5-14(27)28)23-19(34)13(7-16(31)32)21-10(3)26/h8-9,11-13,17H,4-7H2,1-3H3,(H,21,26)(H,22,35)(H,23,34)(H,24,33)(H,27,28)(H,29,30)(H,31,32)
UMBVAPCONCILTL-UHFFFAOYSA-N

Informazioni sul gene

human ... CASP1(834) , CASP3(836) , CASP7(840) , CASP8(841)

Amino Acid Sequence

NAc-Asp-Glu-Val-Asp-al

Descrizione generale

N-Acetyl-Asp-Glu-Val-Asp-al (Ac-DEVD-CHO) is a tetrapeptide with N-terminal acetylation and C-terminal aldehyde conjugation.

Applicazioni

N-Acetyl-Asp-Glu-Val-Asp-al has been used as a caspase inhibitor in muscle samples, smooth muscle cells and Jurkat T-cells.

Azioni biochim/fisiol

N-Acetyl-Asp-Glu-Val-Asp-al (Ac-DEVD-CHO) aids in the recovery of stunned myocardium by its caspase inhibition functionality.
Reversible inhibitor of IL-1β converting enzyme (ICE); inhibits poly(ADP-ribose) polymerase cleavage by apopain (caspase 3).

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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NSCI ≥97% (HPLC), solid

Sigma-Aldrich

N1413

NSCI

Caspase 3 Substrate (PKC), chromogenic

Sigma-Aldrich

SCP0085

Caspase 3 Substrate (PKC), chromogenic

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Sigma-Aldrich

218759

Caspase-8 Inhibitor II

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Sigma-Aldrich

A9968

N-Acetyl-Ile-Glu-Thr-Asp-p-nitroanilide

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