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CdO/CdA

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69125

Resorufin methyl ether

Name: Resorufin methyl ether
Brand: SIGMA

suitable for fluorescence, ≥98.0% (HPLC)

Sinonimo/i:

7-Methoxy-3H-phenoxazin-3-one, Methoxyresorufin, O⁷-Methylresorufin

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About This Item

Formula empirica (notazione di Hill):

C₁₃H₉NO₃

Numero CAS:

5725-89-3

Peso molecolare:

227.22

Beilstein:

209529

Numero MDL:

MFCD00037663

Codice UNSPSC:

12352200

ID PubChem:

57652175

Saggio

≥98.0% (HPLC)

Forma fisica

crystals

Punto di fusione

≥220 °C (lit.)

Solubilità

DMF: soluble
DMSO: soluble
alcohols: soluble

Fluorescenza

λ_ex 571 nm; λ_em 585 nm in dealkylase(lit.)

Compatibilità

suitable for fluorescence

Temperatura di conservazione

2-8°C

Stringa SMILE

COc1ccc2N=C3C=CC(=O)C=C3Oc2c1

InChI

1S/C13H9NO3/c1-16-9-3-5-11-13(7-9)17-12-6-8(15)2-4-10(12)14-11/h2-7H,1H3
KNYYMGDYROYBRE-UHFFFAOYSA-N

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Applicazioni

Used to differentiate isozymes of cytochrome P-450

Confezionamento

Bottomless glass bottle. Contents are inside inserted fused cone.

Codice della classe di stoccaggio

13 - Non Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

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Sigma-Aldrich

90101

Ampliflu^™ Red

Sigma-Aldrich

R7017

Resazurin sodium salt

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Toxicology and applied pharmacology, 234(3), 306-313 (2008-12-02)

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Alteration of the pharmacokinetics of theophylline by rutaecarpine, an alkaloid of the medicinal herb Evodia rutaecarpa, in rats.

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The Journal of pharmacy and pharmacology, 57(2), 227-232 (2005-02-22)

Rutaecarpine is a main active alkaloid present in the medicinal herb, Evodia rutaecarpa. The cytochrome P450 (CYP) 1A2 substrate, theophylline, is an important therapeutic agent for the treatment of asthma, but has a narrow therapeutic index. To evaluate the pharmacokinetic

Inhibition of human and rat CYP1A2 by TCDD and dioxin-like chemicals.

D F Staskal et al.

Toxicological sciences : an official journal of the Society of Toxicology, 84(2), 225-231 (2005-01-22)

Dioxins have been shown to bind and induce rodent CYP1A2, producing a dose-dependent hepatic sequestration in vivo. The induction of CYP1A2 activity has been used as a noninvasive biomarker for human exposure to dioxins; while there is a consistent relationship

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